HAI 2026 POSTER SESSIONS
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Please note that we reserve the right to re-arrange the poster allocation.
POSTER SESSIONS: 1A - Monday, January 12 - 10:30 am - 11:30 pm; 1B - Monday, January 12, 4:20 - 5:20 pm
| Board # | Title | Authors | Presenter |
|---|---|---|---|
| 01 | Longitudinal harmonization effects on tau-PET SUVRs trajectories in ADNI study | Ren | Luo | Laymon | Minhas | Cohen | Wu | Tudorascu | Ren, Yuxin |
| 02 | Integrating digital cognitive metrics with PET biomarkers to identify individuals at imminent risk of tau accumulation | Fu | Robinson | Farrell | Jutten | Thibault | Thompson | Tiss | Chen | Becker | Healy | Penney | Davis | Sperling | Price | Rentz | Johnson | Fu, Jessie Fang-Lu |
| 03 | Amyloid-induced neuronal hyperactivity and metabolism are associated with faster tau accumulation in Alzheimer’s Disease | Roemer-Cassiano | Zhang | Evangelista | Klonowski | Hirsch | Frontzkowski | Steward | Dewenter | Biel | Zhu | Gnoerich | Jaekel | Hoeglinger | Brendel | Yeo | Franzmeier | Roemer-Cassiano, Sebastian |
| 04 | Sex differences in white matter microstructure and associations with amyloid and tau pathology in autosomal dominant Alzheimer's disease | Giudicessi | Koops, PhD | Baena | Alvarez | Vidal | Martinez | Gonzalez | Tristão-Pereira | Malotaux | He | Aguillon | Jacobs | Cronin-Golomb | Quiroz | Giudicessi, Averi |
| 05 | Concordance between amyloid PET and biomarkers of Alzheimer’s disease in plasma and cerebrospinal fluid in cognitively unimpaired individuals | Bermudez | Fought | Hofrenning | Lowe | Petersen | Vemuri | Jack, Jr. | Algeciral-Schimnich | Bornhorst | Graff-Radford | Bermudez, Camilo |
| 06 | Comparing performance of different amyloid PET markers of spatial extent in their ability to predict future amyloid conversion | Honhar | Farrell | Properzi | Thibault | Schultz | Becker | Fu | Sperling | Price | Johnson | Honhar, Praveen |
| 07 | Elevated ptau217 is more strongly associated with tau accumulation and cognitive decline in younger adults | Coughlan | Townsend | Li | Seto | Birkenbihl | Cody | Klinger | Healy | Farrell | Thibault | Rissman | Properzi | Schultz | Chhatwal | Yang | Donohue | Betthauser | Johnson | Johnson | Sperling | Buckley | Coughlan, Gillian |
| 08 | Quantitative relationship between Lumipulse G measures of pTau217 in plasma and in brain | Vandenberghe | Tomé | De Meyer | Goossens | Lambrechts | Poesen | Vanbrabant | Vanmechelen | Thal | Vandenberghe, Rik |
| 09 | Distinct mechanisms underlying APOE-ε4 and sex effects on medial temporal tau pathology: A neuropathology study | Salvadó | Groot | Wisse | Vogel | Beach | Serrano | Reiman | Schneider | Bennett | Ossenkoppele | Hansson | Salvadó, Gemma |
| 10 | Harmonizing amyloid PET tracers at the regional level: evaluation of regional centiloid equations | Silvestri | Chaggar | Gobbi | Aldea | Klein | Tonietto | Tonietto, Matteo |
| 11 | A case series of lecanemab treatment response in patients across the clinical phenotypic spectrum of AD | Corriveau-Lecavalier | Machulda | Fields | Boots | Whitwell | Day | Aduen | Frank | Kremers | Ramanan | Graff-Radford | Lowe | Boeve | Knopman | Petersen | Jack | Stricker | Jones | Corriveau-Lecavalier, Nick |
| 12 | Validation of a pseudo-reference region for [11C]-ER176 in healthy volunteers and Alzheimer’s disease patients | Finn | Zanotti-Fregonara | Yu | Masdeu | Pascual | Finn, Quentin |
| 13 | β-amyloid PET signal reduction is higher in regions with ARIA-E due to anti-amyloid therapy | Finn | Pascual | Toledo | Schulz | Masdeu | Finn, Quentin |
| 14 | Lifetime and 10-year absolute risk of cognitive impairment associated with amyloid PET severity: a retrospective, longitudinal cohort study | Hu | Therneau | Wiste | Knopman | Vemuri | Graff-Radford | Lowe | Vassilaki | Cogswell | Schwarz | Algeciras-Schimnich | Petersen | Jack Jr. | Hu, Mingzhao |
| 15 | Trajectory of neurodegeneration and brain aging in relation to amyloid timing and duration | Zhang | Robb | Erus | Castellano | Cui | Cody | Harrison | Engelman | Albert | Resnick | Sperling | Bilgel | Vardarajan | Mayeux | Risacher | Arfanakis | Tosun | Habes | Wang | Toga | Thompson | Kukull | Biber | Landman | Bendlin | Johnson | Schneider | Barnes | Bennett | Saykin | De Jager | Menon | Harrison | Mormino | Cuccaro | Davatzikos | Betthauser | Archer | Hohman | Dumitrescu | Koran | Zhang, Mengna |
| 16 | Associations between tau pathology and cortical microstructure are modulated by amyloid burden independent of cortical atrophy in cognitively unimpaired older adults | Vogt | Koops | Schultz | Properzi | Salat | Pascual-Leone | Huang | Buckley | Rentz | Johnson | Sperling | Jacobs | Vogt, Nicholas |
| 17 | Predicting tau PET burden using brain-derived plasma p-tau measures in the British 1946 birth cohort | Schott | Coath | Wiltshire | Brown | Cash | Whittington | Heslegrave | Zetterberg | Keshavan | Schott, Jonathan |
| 18 | Association of combined cardiovascular risk factors and treatments with longitudinal amyloid and tau PET in cognitively normal older adults | Ourry | Thériault-Dubé | Breitner | Poirier | Villeneuve | Ourry, Valentin |
| 19 | Amyloid-pet substantiates clinical decision-making in real-life clinical settings in Brazil | Schaffer Aguzzoli | Flach | Alves Da Silva | C.L Ferreira | Povala | Ferrari-Souza | Bieger | Teixeira Leffa | Bellaver | Guevara Werlang | Teribele Venturin | Wetters Portuguez | Possa Marroni | Irigoyen da Costa | Bernardi Soder | Sebastião Matushita | Juarez Amorim | Pasquotto Souza | Dario Ramos | Leite | Hygino | Amorim Nogueira | Sturzeneker Tres | Okada de Oliveira | Moriguchi Jeckel | Cortes Domingues | Mosci | Rosado de Castro | Buchpiguel | Paiva Proença Lobo Lopes | Carvalho Campos Neto | Figueiredo Balthazar | Tovar Moll | Martins Novaes Coutinho | Pascoal | Zimmer | Schilling | Costa da Costa | Schaffer Aguzzoli, Cristiano |
| 20 | Neuropathological validation of Tau-PET CenTauR units: Preliminary data from a multicenter study | Iaccarino | Chiotis | Grinberg | Kotari | La Joie | Leuzy | Lowe | Lu | Moscoso | Nguyen | Schwarz | Seeley | Jack | Rabinovici | Shcherbinin | La Joie, Renaud |
| 21 | Molecular evaluation of a tau-PET analog and pathological TAR DNA-binding protein 43 docking in a cellular model of frontotemporal lobar degeneration | Gatto | Weissmann | Salinas Castellanos | Montes | Uruk | Youssef | Reichard | Josephs | Gatto, Rodolfo G. |
| 22 | Anterior cingulate sulcal pattern is associated with successful cognitive aging | Maboudian | Kellerman | Willbrand | Pezzoli | Weiner | Jagust | Maboudian, Samira |
| 23 | Microstructural white matter injury mediates the association between vascular risk and plasma biomarkers: Preliminary findings from the Diverse VCID study | Lee | Sapkota | Rajan | Jin | Hinman | Johnson | Harvey | Maillard | Fornage | DeCarli | Lee, Seunghoon |
| 24 | VeraBIND Tau: a novel plasma assay reflecting tau aggregation increases over time in individuals with positive tau-PET signal | Hanseeuw | Quenon | Bayart | Salman | Pak | Shamsundar | Soldo | Iqbal | Hanseeuw, Bernard |
| 25 | Amyloid PET quantitation using skewness: Autopsy validation and test–retest performance | Tunali | Iaccarino | Wang | Kennedy | Lu | Shcherbinin | Tunali, Ilke |
| 26 | Stratifying preclinical Alzheimer’s disease by hippocampal volume to detect concomitant LATE | Mundada | Lyu | Sadeghpour | Brown | McGrew | Yushkevich | Das | Wolk | Mundada, Nidhi |
| 27 | Differential sensitivity of [¹⁸F]MK6240 and [¹⁸F]FTP to measure tau before and after anti-amyloid therapy | Deng | Finn | Pando | Matutue | Lussier | Fortea | Tudorascu | Soleimani-Meigooni | Lowe | Oh | Gordon | Rosa-Neto | Baker | Pascoal | Masdeu | Pascual | Deng, Han |
| 28 | Development of a highly sensitive and automated immunoassay for Brain-Derived pTau-217: Analytical performance in human plasma samples | Ma | Wang | Danthanarayana | Kim | Ji | Jhaveri | Zhang | Qiu | Mudumba | Luo | Ma, Xiao-Jun |
| 29 | Network-based mechanistic modeling of Alzheimer's disease for evaluating diverse therapeutic mechanisms of action | Wooten | Stage | Mazer | Townsend | Comley | Guo | Wooten, Dustin |
| 30 | Neuroimaging compendium of microglia, amyloid, tau, and neurodegeneration across clinical variants of Alzheimer's disease | Houlihan | Guzman | Smith | Sanchez | Kreisl | Cosentino | Noble | Lao | Houlihan, Hannah |
| 31 | Predictors of longitudinal atrophy across NIA-AA biological PET stages | Fonseca | Maboudian | Chao | Jagust | Harrison | Fonseca, Corrina |
| 32 | Effect of uptake time on [18F]-flutemetamol visual interpretation and Centiloid quantification | Bollack | Buckley | Schwarz | Battle | Smith | Stromrud | Hansson | Palmqvist | Matttsson-Carlgren | La Joie | Farrar | Bollack, Ariane |
| 33 | Episodic memory decline and tau biomarkers progress earlier along the amyloid timeline in Down syndrome compared to neurotypical adults | Zammit | Bruzzone | Morse | Batchelar | Bettcher | McLachlan | McVea | Carey | Tudorascu | Hartley | Clark | Ances | Caldwell | Johnson | Handen | Head | Mapstone | Christian | Investigators | Betthauser | Zammit, Matt |
| 34 | Relationship between p-tau217 and PET in preclinical AD: The moderating effect of white matter hyperintensity | Moon | Chen | Moon, Hasom |
| 35 | Systemic inflammation–tau interaction: Insights from CRP modulation of p-tau217 association with tau PET positivity | Monto | Boots | Zeng | Farinas | Sehrawat | Saeed | Cohen | Reis | Lopez | Snitz | Karikari | Monto, Abdul Razak |
| 36 | Examining elevated choroid plexus binding of tau PET tracers in aging and Alzheimer’s disease | Marin | Wales | Ruais | Richard | Hedden | Marin, Anna |
| 37 | The influence of β-amyloid on neuroinflammatory 11C-ER176 uptake in progressive apraxia of speech | Satoh | Utianski | Duffy | Clark | Botha | Lowe | Josephs | Whitwell | Satoh, Ryota |
| 38 | Subtracting first principal component may improve detectability of subtle 4R tau signals in 18F flortaucipir tau PET imaging | Satoh | Ali | Clark | Dickson | Lowe | Josephs | Whitwell | Satoh, Ryota |
| 39 | OMG: a proteomic determinant of neurodegenerative resiliency | Duggan | Oh | Frank | Gomez | Zweibaum | Cui | Chen | Surapaneni | Blew | Dark | Joynes | Kandala | Bilgel | Farinas | Erus | Tian | Candia | Pucha | Landman | Dumitrescu | Hohman | Lewis | Moghekar | Siavoshi | Ali | Liu | Xu | Western | Kaneko | Kato | Furuichi | Shibayama | Katsuno | Nishita | Otsuka | Gottesman | Dammer | Seyfried | Levey | Johnson | Mormino | Wagner | Poston | Kapogiannis | Grams | Bhargava | Waga | Davatzikos | Resnick | Ferrucci | Bennett | Cruchaga | Wyss-Coray | Kivimäki | Coresh | Walker | Duggan, Michael |
| 40 | Frequency and consequences of extreme PET based pathological profiles in preclinical Alzheimer’s disease | Medina Guerra | Cody | Young | Sheng | Sokolowski | Younes | Trelle | Tosun | Hohman | Mormino | Medina Guerra, Lucah |
| 41 | Periventricular diffusivity moderates the relationship between astrocyte reactivity and amyloid deposition in non-demented older adults | Chen | Wu | Yang | Gogola | Luo | Villemagne | Laymon | Lopresti | Cohen | Ikonomovic | Snitz | Wilckens | Lopez | Tudorascu | Aizenstein | Minhas | Chen, Chang-Le |
| 42 | Disentangling the effects of age and Alzheimer's disease pathology on longitudinal atrophy in cognitively normal older adults | Haque | Fonseca | Maboudian | La Joie | Jagust | Haque, Miraal |
| 43 | Stronger amyloid–tau coupling explains faster tau progression in early-onset Alzheimer’s disease | Franzmeier | Frontzkowski | Steward | Klonowski | Dewenter | Hirsch | Biel | Zhu | Gnörich | Höglinger | Brendel | Roemer-Cassiano | Franzmeier, Nicolai |
| 44 | Harmonization methods to mitigate batch effects in blood biomarker analysis | Zhang | Lukasewicz Ferreira | Minhas | Pascoal | Zeng | Karikari | Cohen | Tudorascu | Zhang, Vivian |
| 45 | IGFR1, but not BDNF, acts as a suppressive neuroprotective factor between astrogliosis and visuospatial function among non-demented individuals | Ramirez Tirado | Cohen | Lopresti | Ikonomovic | Gogola | Matan | Zeng | Karikari | Lopez | Shaaban | Villemagne | Cohen, Ann D |
| 46 | The relation of psychosocial coping mechanisms to ATN pathophysiology differ across demographics | Schatz | Snitz | Roush | Lopresti | Villemagne | Lopez | Williams | Cohen | Cohen, Ann |
| 47 | Evaluation of the Clinical IMpact of Blood-Based Biomarker Assays on dementia specialists' decision-making (CIMBBBA): Preliminary report from a real-world dementia subspecialty clinic study | Eldaief | Krahn | Murdock | Rezaii | Chan | Arnold | Avetisyan | Ramirez Gomez | Gale | McGinnis | Dickerson | Eldaief, Mark |
| 48 | Dynamic interplay of vascular injury and inflammation on Alzheimer’s disease pathophysiology | Rusdi | Kang | Yin | Gibson | Rahmouni | Benedet | Zetterberg | Blennow | Karikari | Ashton | Black | Rosa-Neto | Goubran | Ottoy | Ottoy, Julie |
POSTER SESSIONS: 2A - Tuesday, January 13 - 09:50 - 10:50 am; 2B - Tuesday, January 13, 3:40 - 4:40 pm
| Board # | Title | Authors | Presenter |
|---|---|---|---|
| 49 | CSF oligodendrocyte biomarkers are associated with amyloid burden in Alzheimer’s disease | Santos Machado | De Bastiani | Lebrun | Povala | Pola | Vizlin-Hodzic | Rosa-Neto | Zimmer | Blennow | Zetterberg | Benedet | Ashton | Santos Machado, Luiza |
| 50 | Associations between systolic blood pressure and amyloid burden on cross-sectional inferior temporal tau across mid- to late-life | Yau | Scott | Palmgren | Coughlan | Kirn | Properzi | Schultz | Ghosh | Buckley | Amariglio | Rentz | Johnson | Sperling | Beiser | Seshadri | Chhatwal | Yau, Wai-Ying Wendy |
| 51 | Associations of ER176 TSPO PET with blood-based AD and neuroinflammation biomarkers | Cogswell | Lundt | Ou | Algeciras-Schimnich | Zekeridou | Lim | Graff-Radford | Schwarz | Vemuri | Petersen | Jack Jr | Lowe | Cogswell, Petrice |
| 52 | Evaluation of [18F]MK6240 test-retest reproducibility for different processing pipelines | Tiss | Thibault | Fu | Becker | Price | Johnson | Tiss, Amal |
| 53 | Temporal dynamics of tau PET subtypes and its association with heterogeneous neurodegeneration in Alzheimer’s disease | Kwon | Song | Lee | Seong | Kwon, Tae Youn |
| 54 | A-T-N-C generative model for predicting and simulating patient-tailored cognitive decline trajectories in Alzheimer’s disease | Lee | Song | Kwon | Lee | Seong | Kwon, Tae Youn |
| 55 | High-resolution ex-vivo MRI reveals layer-specific atrophy of hippocampal subregions to earliest tau pathology | Salman | Tomé | Joudiou | Thal | Annettesdotter | Khandelwal | Yushkevich | Gallez | Wisse | Hanseeuw | Salman, Yasmine |
| 56 | Blood volume influences the association between baseline plasma biomarker values and amyloid PET outcomes over time | Burns | Gogola | Zeng | Karikari | Jacobs | Lopresti | Osorio | Burns, Kelsey |
| 57 | Visual interpretation methods for tau-PET imaging with Flortaucipir and MK-6240: Insights from the HEAD study | Ruppert | Vermeiren | Scop Medeiros | Povala | Rocha | Soares | Ferreira | Amaral | Bauer-Negrini | Lussier | Scarpatto Rodrigues | Oliveira Jr. | Mroue | Bellaver | Moscoso | Ossenkoppele | van de Giessen | Masdeu | Tudorascu | Soleimani-Meigooni | Fortea | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Pascoal | Pascoal, Tharick |
| 58 | Associations between TSPO PET and CSF and blood-based biomarkers | Smith | Guzman | Houlihan | Sanchez | Kreisl | Talmasov | De Jager | Herman | Simoes | Small | Lao | Smith, Anna |
| 59 | Regional white matter injury modifies the association between ß-amyloid and cognition | Royse | Reese | Snitz | Hengenius | Crane | Mukherjee | Choi | Willie-Permor | Felix | Huppert | Roush | Cisneros | Potopenko | Lopresti | Cohen | Shaaban | Royse, Sarah |
| 60 | Sex differences in neuroinflammation, amyloid, tau, and neurodegeneration | Guzman | Smith | Houlihan | Sanchez | Akinci | Luchsinger | Lao | Guzman, Diana |
| 61 | Evaluation of the tau PET ligand [18F]florzolotau in frontotemporal dementia | Clarke | Whittington | Sholaja | Hield | Huiban | van den Berg | Margolin | Rowe | Rohrer | Salinas | Rabiner | Whittington, Alex |
| 62 | Intersections of gender/sex and neighborhood deprivation on cognition: Are there mediation effects of Alzheimer's disease biomarkers? | Reese | Royse | Snitz | Crane | Mukherjee | Choi | Hengenius | Huppert | Roush | Cisneros | Lopresti | Rameriz Tirado | Willie-Permor | Felix | Cohen | Shaaban | Reese, Alexandria |
| 63 | Disentangling cognitive severity and phenotype across dementia syndromes | Smith | Coyle-Gilchrist | Murley | Rouse | Stockton | Naessens | Savulich | Wiggins | Malpetti | Bowns | Perquin | Lanskey | Karadag | Kocagoncu | Quinn | Pitt | Alcock | O'Brien | Rittman | Rowe | Lambon-Ralph | Smith, Viktorija |
| 64 | Standardized indices of tau burden using the CenTauR universal scale predict distinct cognitive trajectories across Alzheimer’s disease biological stages | Lopresti | DelBene | Leuzy | Gogola | Harrison | Landau | Jagust | Villemagne | Lopresti, Brian |
| 65 | SPARE-SVD: An integrated machine-learning metric for cerebral small vessel disease within the ATN(V) framework | Dong | Zhang | Zeng | Wang | Wang | Toledo | Gonzales | Charisis | Rashid | Seshadri | Crane | Archer | Jefferson | Hohman | Habes | Dong, Mengjin |
| 66 | Risk factors and AD prevention: a multivariate and multimodal study | Fajardo Valdez | Qiu | Ourry | Yakoub | Villeneuve | Research Group | Fajardo Valdez, Alfonso |
| 67 | MK6240 and Tauvid positivity, cognitive decline, and their relationship to Aβ PET deposition across the Alzheimer’s spectrum | Bellaver | Povala | Lussier | Amaral | Bauer-Negrini | Ferreira | Jagust | Masdeu | Fortea | Tudorascu | Soleimani-Meigooni | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Pascoal | Bellaver, Bruna |
| 68 | Differential tau-PET load predominance along shared progression trajectories determines clinical variability in Alzheimer’s disease | Mroué | Povala | Bellaver | Lukasewicz Ferreira | Bauer-Negrini | Lussier | Amaral | Scop Medeiros | Ruppert | Silva da Rocha | Scarpatto Rodrigues | Silva Oliveira | Soares Katz | Teixeira Leffa | Saha | Masdeu | Soleimani-Meigooni | Fortea | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Pascoal | Povala, Guilherme |
| 69 | Head-to-head comparison of tau PET tracers across the Alzheimer’s disease spectrum: baseline results from the HEAD study | Povala | Bellaver | Lussier | Amaral | Bauer-Negrini | Ferreira | Jagust | Masdeu | Fortea | Tudorascu | Soleimani-Meigooni | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Pascoal | Povala, Guilherme |
| 70 | Comparison of Sampled Iterative Local Approximation (SILA) implemented in R and MATLAB | Bruzzone | Coath | Navaratna | Carey | Morse | Bilgel | Betthauser | Bruzzone, Hailey |
| 71 | Agreement between amyloid status prediction from visual read, SUVR thresholding, and AI-based interpretation of amyloid PET | Peraza | Joules | Mohs | Beauregard | Dwyer | Hughes | Wolz | Wolz, Robin |
| 72 | CenTauR thresholds generated using Gaussian Mixture Models for biological staging of amyloid positive ADNI participants | DelBene | Villemagne | Gogola | Leuzy | Harrison | Landau | Jagust | Lopresti | DelBene, Alexander |
| 73 | Progression to tau-PET positivity by plasma P-tau217 levels and its association with clinical decline in preclinical Alzheimer’s disease: data from A4 study | Kim | Kotari | Morris | Shcherbinin | Yaari | Holdridge | Sims | Ossenkoppele | Collins | Hansson | Lu | Kim, Min Jung |
| 74 | Neuroimaging correlates of loneliness | Sanchez | Guzman | Smith | Houlihan | Stern | Bockting | Lao | Sanchez, Thairi |
| 75 | Age-dependent associations between salivary inflammatory cytokines and amyloid-beta in cognitively unimpaired older adults | Parker | Tang | Taylor | Bock | Meza | Tuteja | Avila | Chang | Simmons | Bamford | Yi | Mcmillan | Kim | Thomas | Adams | Yassa | Parker, Dana |
| 76 | Tau accumulation drives worsening depressive symptoms in cognitively normal older adults | Markova | Berry | Markova, Teodora |
| 77 | Dorsal raphe nucleus and locus coeruleus differentially relate to depressive symptoms in cognitively normal older adults | Markova | Chen | Carlson | Cao | Ciampa | Marcus | Adornato | Matulonis | Morin | Hooker | Berry | Markova, Teodora |
| 78 | Evaluating occipital-to-global amyloid PET as a predictor of CAA at autopsy in Mayo Clinic cohorts | Schwarz | Hu | Cogswell | Graff-Radford | Vemuri | Przybelski | Wiste | Nguyen | Reichard | Dickson | Lowe | Ramanan | Knopman | Petersen | Jack | Schwarz, Christopher |
| 79 | SCAN: Standardized Centralized Alzheimer’s and related dementias Neuroimaging | Schwarz | Harrison | DeCarli | Kantarci | Baker | La Joie | Maillard | Rabinovici | Toga | Jack | Jagust | Schwarz, Christopher |
| 80 | Differential contributions of amyloid spatial extent and tau burden to domain-specific cognitive decline in early Alzheimer’s disease | Slade | Thibault | Thompson | Fanglu Fu | Price | Rentz | Sperling | Johnson | Farrell | Slade, Elliott |
| 81 | PET-measured amyloid accumulation rate modulates tau accumulation rate in individuals with Down syndrome | Bettcher | McLachlan | Zammit | McVea | Betthauser | Laymon | Tudorascu | Cohen | Price | Head | Mapstone | Lao | Johnson | Ances | Handen | Christian | Bettcher, Brecca |
| 82 | Elevated medial temporal lobe tau predicts cross-sectional association between neocortical tau and global amyloid burden | Thibault | Reilhac-Laborde | Charil | Irizarry | Johnson | Thibault, Emma G. |
| 83 | Assessing the effect of amyloid status on the relationship between glucose metabolism and synaptic density in the aging population | McLachlan | Bettcher | DiFilippo | LeMerise | McVea | Zammit | Langhough | Johnson | Bendlin | Christian | McLachlan, Max |
| 84 | Associations between p-tau217 and brain atrophy are amplified by Aβ burden and APOEε4 | Brown | Properzi | Cuppels | Birkenbihl | Coughlin | Seto | Townsend | Betthauser | Schultz | Chhatwal | Yang | Jacobs | Farrell | Johnson | Johnson | Li | Sperling | Hohman | Donohue | Buckley | Brown, Jane |
| 85 | Early cortical thickness change in preclinical AD development | Sinclair | Chen | Sinclair, Stephanie |
| 86 | Immuno-vascular crosstalk drives tau pathology preferentially in women | Wood Alexander | Kang | Rusdi | Yin | Rahmouni | Wang | Benedet | Zetterberg | Blennow | Karikari | Ashton | Black | Goubran | Rabin | Ottoy | Wood Alexander, Madeline |
| 87 | Midlife physical activity attenuates the association of earlier menopause with tau pathology and cognitive decline | Wood Alexander | Cadwallader | Johnson | Casaletto | Rabin | Wood Alexander, Madeline |
| 88 | Improved tau PET signal detection with total-body PET compared to conventional PET: A preliminary study | Young | Bayerlein | Bhattarai | DeCarli | Badawi | Fan | Young, Christina |
| 89 | Demographic associations with plasma biomarkers in the oldest-old: The LifeAfter90 Study | Young | Colbeth | Gilsanz | Corrada | Rizvi | Zhou | di Lucente | DeCarli | Jin | Whitmer | Young, Christina |
| 90 | Differential sensitivity of T1-MRI and FDG-PET for tracking neurodegeneration across progressive stages of tau pathology in Alzheimer’s disease | Vourkas | Karagianni | Moscoso | Zhang | Sanchez-Juan | Schöll | Grothe | Silva-Rodríguez | Silva-Rodríguez, Jesús |
| 91 | SPARE-Tau, a machine-learning derived tau-PET index, correlates with Alzheimer's disease and related dementias biomarkers | Wang | Zeng | Toledo | Gonzales | Honnorat | Charisis | Dong | Ho | Rashid | Kutty | Salman | Vroman | Seshadri | Habes | Wang, David |
| 92 | Assessing the generalizability of plasma p-tau217 cutpoints for amyloid-β detection across clinical and preclinical cohorts | Liu | Zeng | Nafash | Sehrawat | Choity | Gu | Farinas | Bedison | Matan | Gogola | Huang | Sewell | McAuley | Hillman | Kramer | Burns | Kang | Vidoni | Nadkarni | Aizenstein | Kofler | Tudorascu | Shaaban | Lingler | Pascoal | Villemagne | Berman | Sweet | Snitz | Ikonomovic | Kamboh | Erickson | Cohen | Lopez | Deek | Karikari | Liu, Tianshu |
| 93 | Evaluating the transferability of dual cutpoints for plasma p-tau217 in detecting brain amyloid-β across diverse cohorts | Liu | Zeng | Nafash | Sehrawat | Choity | Gu | Farinas | Bedison | Matan | Gogola | Huang | Sewell | McAuley | Hillman | Kramer | Burns | Kang | Vidoni | Nadkarni | Aizenstein | Kofler | Tudorascu | Shaaban | Lingler | Pascoal | Villemagne | Berman | Sweet | Snitz | Ikonomovic | Kamboh | Erickson | Cohen | Lopez | Deek | Karikari | Liu, Tianshu |
| 94 | Free-water interacts with amyloid positivity to predict regional tau pathology in both early and late Braak stages | Sathe | Durant | Koran | Dumitrescu | Cody | Sokołowski | Kim | Mez | Saykin | Toga | Cuccaro | Tosun | Johnson | Barber | O'Bryant | Landman | Mormino | Hohman | Archer | Sathe, Aditi |
| 95 | Integration of data-driven biomarker discovery with established Alzheimer’s disease biomarkers in an African American cohort | Kuchenbecker | Heckman | Nguyen | Casellas | Sotelo | Schwarz | Senjem | Jain | Lucas | Willis | Ertekin-Taner | Graff-Radford | Kantarci | Lowe | Lachner | Day | Carrasquillo | Kuchenbecker, Lindsey |
| 96 | Early concordance between Aβ PET spatial extent and plasma %ptau217 | Farrell | Thibault | Yang | Price | Chhatwal | Coughlan | Buckley | Sperling | Johnson | Farrell, Michelle |
POSTER SESSIONS: 3A - Wednesday, January 14, 10:35 - 11:35 am; 3B - Wednesday, January 14, 2:45 - 3:45 pm
| Board # | Title | Authors | Presenter |
|---|---|---|---|
| 97 | Longitudinal trajectories of plasma p-tau217 across multiple assays in relation to amyloid and tau PET and cognition | Shekari | Tosun | Dage | Schindler | Shaw | Jagust | Landau | Shekari, Mahnaz |
| 98 | The relation of psychosocial coping mechanisms to ATN pathophysiology differ across demographics. | Schatz | Snitz | Roush | Lopresti | Villemagne | Lopez | Williams | Cohen | Williams, Lilcelia A. |
| 99 | Intermediate blood-based biomarker status clarified by PET and CSF in cognitively impaired individuals | Ziontz | Blazhenets | Lin | Landau | Shaw | Dage | Hammers | Eloyan | Koeppe | Carillo | Dickerson | Rabinovici | La Joie | Ziontz, Jacob |
| 100 | Operationalizing clinical criteria for LATE using cognitive, MRI, and AD biomarker (biofluid or PET) data | Cuppels | Birkenbihl | Schneider | Bennett | Brown | Seto | Coughlan | Li | Townsend | Properzi | James | Arfanakis | Sperling | Yang | Chhatwal | Amariglio | Hohman | Donohue | Buckley | Cuppels, Madison |
| 101 | CT-based processing is equivalent to MR-based processing for tau PET regional quantification | Povala | Bellaver | Amaral | Lussier | Ferreira | Bauer-Negrini | Tudorascu | Masdeu | Fortea | Soleimani-Meigooni | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Pascoal | Povala, Guilherme |
| 102 | A pilot study on the association of plasma proteins with neuroimaging biomarkers of Alzheimer’s disease in African Americans | Arowolo | Kuchenbecker | Heckman | Nguyen | Casellas | Sotelo | Schwarz | Senjem | Jain | Lucas | Willis | Ertekin-Taner | Graff-Radford | Kantarci | Lowe | Lachner | Day | Carrasquillo | Arowolo, Olatunbosun |
| 103 | Amyloid-PET and white matter hyperintensities but not military service duration nor combat exposure are associated with neurodegeneration and cognitive impairment in older veterans | Rocha | Pasternak | Lesman Segev | Schwartz | Blazhenets | Maiti | Rosen Lang | Hantke | Livny-Ezer | Yaffe | Shaw | Weiner | Hills | Kritikos | Soleimani-Meigooni | Silbert | La Joie | Gardner | Rocha, Salma |
| 104 | The influence of cardiovascular risk on white matter integrity along the Alzheimer’s disease trajectory: Early impact in preclinical stages | Edison | Arnold | Edison, Paul |
| 105 | Longitudinal tau PET progression follows language network spread in primary progressive aphasia | Martersteck | Rogalski | Martersteck, Adam |
| 106 | The adjusted Centiloid: Improving reliability by correcting for white matter uptake variability | Reilhac | Irizarry | Reyderman | Charil | Reilhac, Anthonin |
| 107 | Perivascular spaces: Predictors of longitudinal amyloid, tau, cerebrovascular biomarkers? | Low | Gunter | Hu | Raghavan | Przybelski | Schwarz | Kantarci | Lowe | Graff-Radford | Petersen | Jack | Vemuri | Low, Audrey |
| 108 | Longitudinal evaluation of neuroinflammation using 11C-ER176 TSPO PET | Lim | Cogswell | Min | Lee | Brunn | Kandimalla | Jacobson | Nycklemoe | Lee | Lundt | Botha | Graff-Radford | Jones | Vemuri | Kantarci | Jack | Petersen | Lowe | Lim, Seokbeen |
| 109 | Comparison of meningeal signal between [¹⁸F]AV-1451 and [¹⁸F]MK-6240 tau PET using a distance-based meningeal mask | Lim | Gunter | Baker | Tissot | Brunn | Soleimani-Meigooni | Oh | Fortea | Pascual | Gordon | Rosa-Neto | Pascoal | Klunk | Jagust | Senjem | Botha | Knopman | McCarter | Ramanan | Graff-Radford | Schwarz | Kantarci | Boeve | Vemuri | Jones | Jack | Petersen | Lowe | Lim, Seokbeen |
| 110 | Effects of regional tau accumulation on visual discrimination of novel objects in clinically unimpaired older adults | Kapadia | Medina Guerra | Sai | Bonnen | Wagner | Mormino | Trelle | Kapadia, Dhruv |
| 111 | Key quantitative benchmarks with CenTauR in cross-sectional and longitudinal large datasets | Dore | Bourgeat | Betthauser | Feizpour | Moscoso | Leuzy | Fripp | Johnson | Rowe | Villemagne | Dore, Vincent |
| 112 | Astrocytic reactivity is related to synchronization of regional amyloid-beta deposition | Adams | Parker | Taylor | Tang | Meza | Tuteja | Avila | Chang | Simmons | Malhas | Kim | McMillan | Mapstone | Yassa | Adams, Jenna |
| 113 | Synergistic effects of amyloid-beta and hyperexcitability on tau pathology and cognitive decline | Vanderlip | Adams | Adams, Jenna |
| 114 | Amyloid does not discriminate: a meta-analysis of sex differences in Centiloids from 35,468 participants across 33 cohorts | Blazhenets | Pezzoli | Casaletto | Soleimani-Meigooni | Chiotis | Allen | Rabinovici | La Joie | Study Group | Blazhenets, Ganna |
| 115 | Preliminary associations of plasma phosphorylated tau217 with regional tau deposition and accumulation in medial temporal and neocortical regions | Pintucci | Thibault | Farrell | Yang | Chhatwal | Properzi | Becker | Price | Sperling | Johnson | Pintucci, Eva |
| 116 | Contrasting neuropathology- and tau PET-based Braak stage associations with dementia severity to clarify differences between radiologic and pathologic findings | Evelhoch | Bruzzone | Rocha | Asthana | Nirschl | Johnson | Schneider | Hyman | Pascoal | Betthauser | Evelhoch, Jeffrey |
| 117 | Novel pet tracer [11C]-CS1P1 uptake reflects decreased sphingosine-1-phosphate receptor 1 activity in vivo in Alzheimer’s disease and related dementias | Tiemann Powles | Friedrichsen | Flores | Rajamanickam | Keefe | Simmons | Doering | McKay | Hoagey | Sabaredzovic | Ibanez | Morris | An | Brier | Tu | Benzinger | Tiemann Powles, Savannah |
| 118 | Digital maze test reveals features related to cortical tau in cognitively normal Aβ+ older adults | Robinson | Fu | Amariglio | Sperling | Johnson | Davis | Penney | Rentz | Robinson, Talia |
| 119 | Associations of regional neuroinflammation by ER176 PET SUVR with cognitive scores | Jacobson | Lim | Lundt | Nycklemoe | Min | Botha | Graff-Radford | Jones | Vemuri | Kantarci | Knopman | Jack | Petersen | Lowe | Jacobson, David |
| 120 | Cluster-based metric of early tau-PET aggregation is associated with plasma p-tau217 in cognitively unimpaired older adults with subthreshold amyloid-beta | Varghese | Brock | Taylor | Thomas | Yassa | Adams | Varghese, Leah |
| 121 | Sex differences in regional Aβ burden are associated with decreased cingulum integrity uniquely in older cognitively unimpaired women | Yi | Parker | Tang | Taylor | Tuteja | Meza | Avila | Chang | Simmons | Bamford | McMillan | Kim | Thomas | Adams | Yassa | Yi, Emily |
| 122 | Cerebral vessel morphology is associated with white matter lesions burden | Huang | Li | Rocha | Stetten | Yang | Ibrahim | Wu | Aizenstein | Huang, Yuanzhe |
| 123 | Early ventral temporal tau burden marks functional vulnerability in aging | Sheng | Trelle | Sai | Young | Romero | Park | Vossler | Younes | Davidzon | Wagner | Mormino | Sheng, Jintao |
| 124 | Alignment of antemortem images to postmortem fixed hemibrains using standard neuroimaging tools | Coath | Staruck | Carey | de Chavez | Karas | Abrahamson | Asthana | Johnson | Ikonomovic | Nirschl | Betthauser | Coath, William |
| 125 | Towards a harmonized amyloid clock: centralized image processing and temporal modeling with multiple cohorts and tracers | Coath | Bruzzone | Morse | Navaratna | Hammond | Staruck | Nowinski | Palmer | Kelley | Schwartz | Carey | Betthauser | Coath, William |
| 126 | Cluster-based MK-6240 PET detects early neocortical temporal tau spread | Thompson | Becker | Fanglu Fu | Farrell | Thibault | Slade | Sperling | Price | Johnson | Thompson, Jackson |
| 127 | Gaussian smoothing and partial volume correction modify relationships of tau burden with biological variables in longitudinal multi-site studies of 18F-Flortaucipir PET | Luo | Laymon | Baker | Cohen | Villemagne | Lopresti | Aizenstein | Tudorascu | Minhas | Luo, Weiquan |
| 128 | No detectable association between BDNF Val66Met and hippocampal volume or regional tau PET in ADNI after propensity score matching and ComBat harmonization | Han | Minhas | Laymon | Villemagne | Tudorascu | Han, Yushui |
| 129 | Centiloid and SUVR amyloid harmonization techniques comparisons for head-to-head unequally spaced data | Han | Lopresti | Bourgea | Laymon | Villemagne | Tafti | Minhas | Tudorascu | Han, Yushui |
| 130 | Plasma amyloid beta 42/40 modifies the associations between MRI biomarkers and subsequent cognitive impairment: a neuroimaging-wide longitudinal study in the BLSA | Duran | Bilgel | An | Kandala | Davatzikos | Landman | Erus | Ferrucci | Moghekar | Walker | Resnick | Duran, Tugce |
| 131 | High-resolution NAV template using the Siemens Biograph Vision | Bourgeat | Rowe | Paranawithana | Feizpour | Huang | Villemagne | Fripp | Dore | Rowe, Christopher |
| 132 | Higher clinical throughput quantitative amyloid-β PET using abbreviated acquisition windows | Paranawithana | Gillman | Bourgeat | Fripp | Villemagne | O’Keefe | Huang | Benzinger | LaMontagne | Morris | Doré | Rowe | Rowe, Christopher C. |
| 133 | Tracer-specific effects of hormone replacement therapy on age-related tau accumulation | Tissot | Shi | Tsai | Maboudian | Fonseca | Rahmouni | Lussier | Therriault | Trudel | Cassa Macedo | Stevenson | Bellaver | Ferreira | Povala | Gordon | Pascual | Lowe | Soleimani-Meigooni | Oh | Klunk | Rosa-Neto | Jagust | Buckley | Pascoal | Baker | Tissot, Cécile |
| 134 | Cognitive and age-related differences in low-tau individuals assessed with [18F]FTP and [18F]MK6240 | Tissot | Shankar | Tsai | Rahmouni | Lussier | Therriault | Trudel | Cassa Macedo | Stevenson | Bellaver | Ferreira | Povala | Gordon | Pascual | Lowe | Soleimani-Meigooni | Oh | Klunk | Rosa-Neto | Jagust | Landau | Pascoal | Baker | Tissot, Cécile |
| 135 | Integration of network analysis of the plasma proteome with Alzheimer's disease neuroimaging outcomes in an African American cohort | Hurst | Kuchenbecker | Heckman | Nguyen | Casellas | Sotelo | Shwarz | Senjem | Jain | Lucas | Willis | Ertekin-Taner | Graff-Radford | Kantarci | Lowe | Lachner | Day | Carrasquillo | Hurst, Cheyenne |
| 136 | TSPO-mediated mitochondrial dynamics drive microglial activation in early Alzheimer’s disease: Implications for PET-based diagnosis | Lee | Jung | Lim | Lowe | Jung, Dawa |
| 137 | MK6240 and Flortaucipir Braak staging agreement in a head-to-head cohort | Rocha | Soares | Ruppert | Medeiros | Bellaver | Povala | Ferreira | Bauer-Negrini | Lussier | Tudorascu | Masdeu | Soleimani-Meigooni | Fortea | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Pascoal | Pascoal, Tharick |
| 138 | Comparing neuropathologic and tau-PET Braak staging across clinical progression using MK6240 and flortaucipir | Rocha | Bruzzone | Ruppert | Medeiros | Soares | Bellaver | Povala | Ferreira | Lussier | Masdeu | Soleimani-Meigooni | Fortea | Lowe | Oh | Pascual | Gordon | Rosa-Neto | Baker | Johnson | Evelhoch | Betthauser | Pascoal | Pascoal, Tharick |
| 139 | Predictors of data exclusion in MR-dependent imaging analyses of Alzheimer disease | Flores | Scott | Lu | Su | Keefe | Smith | Hornbeck | McKay | Strain | Simmons | Dombrowski | Rizzo | Shimony | Bateman | Babulal | Landau | Jagust | Wolk | Lah | Gleason | Johnson | Roberson | Sperling | Johnson | Morris | Xiong | Gordon | Benzinger | Flores, Shaney |
| 140 | Brain network architecture shapes the pattern of tau-induced neuronal dysfunction in Alzheimer's disease, while tau load drives local damage | Frontzkowski | Roemer-Cassiano | Gnörich | Dewenter | Steward | Zhu | Klonowski | Hirsch | Biel | Palleis | Höglinger | Brendel | Franzmeier | Frontzkowski, Lukas |
| 141 | Cortical thickness and female sex confer resilience to tau-related cognitive decline: A large multi-cohort study | Mitchell | Mitchell, Stuart |
| 142 | Structure-guided design of 18F-FD4—a PET tracer of α-synuclein fibrils | Liu | Li | Wang | Zuo | Tan | Bian | Fan | Liang | Qing, Liang |
| 143 | NULISAseq CNS proteomic signatures of astrocytic reactivity in Alzheimer’s disease | Shi | Zeng | Balogun | Farinas | Lopresti | Gogola | Ikonomovic | Aizenstein | Villemagne | Cohen | Karikari | Shi, Ruyu |
| 144 | High p-tau217 levels nullify the slower cognitive progression in younger older adults | Shi | Choity | Brodman | Zeng | Deek | Gu | Farinas | Nafash | Bedison | Mercurio | Matan | Gogola | Kofler | Tudorascu | Nadkarni | Aizenstein | Shaaban | Lingler | Pascoal | Villemagne | Berman | Sweet | Snitz | Ikonomovic | Cohen | Kamboh | Lopez | Karikari | Shi, Ruyu |
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