HUMAN AMYLOID IMAGING CONFERENCE

The 2021 edition of the conference has been cancelled. We look forward to seeing you in 2022!

HAI 2020 POSTER SESSIONS

Click the “+” to open each module; tables can be sorted by clicking on each item of the header row (board number, poster title, authors and presenter, respectively). Additionally, each table is searchable (use the search field located at the top right of each module).

Please note that we reserve the right to re-arrange the poster allocation.

POSTER SESSIONS: 1A - Wednesday, January 15 - 9:45 - 10:30 am; 1B - Wednesday, January 15, 4:00 - 4:45 pm

BOARD	Title	Author Name	Presenter
1	Label-free x-ray method for estimating brain amyloid load	Badano \| Dahal \| Ghammraoui	Badano
29	Application of an epidemic spreading model to characterize amyloid beta accumulation in dutosomal dominant Alzheimer’s disease mutation carriers	Levitis \| Vogel \| Kiar \| Funck \| Iturria-Medina \| Evans	Levitis
12	Voxel-wise relationships between white matter hyperintensities (WMH) and multimodal neuroimaging biomarkers of Alzheimer’s disease	Gaubert \| Lange \| Garnier-Crussard \| Bougacha \| Gonneaud \| de Flores \| Tomadesso \| Mézenge \| Landeau \| de La Sayette \| Chételat \| Wirth	Lange
46	PET imaging of [11C]MPC-6827, a micrtoubule-based PET tracer in murine models of Alzheimer's disease	Solingapuram sai \| Macauley \| Whitlow \| Mintz \| Craft	Solingapuram sai
4	A pons cluster detected by a data-driven approach may serve as a favorable reference region for 18F-PI-2620 Tau PET analysis	Bischof \| van Eimeren \| Koglin \| Müller \| Bullich \| Perrotin \| Stephens \| Drzezga	Bischof
11	Influence of iron and beta-amyloid deposition on entorhinal cortex and hippocampal subfield volumes in the aging brain	Foster \| Kennedy \| Rodrigue	Foster
17	[11C]PiB amyloid quantification and choice of reference region	Heeman \| Hendriks \| van Berckel \| Lopes Alves \| Lammertsma \| Yaqub	Heeman
47	Quantifying the relationship between the brain distributions of tau and local atrophy to inter-regional connectivity based on individual human data	Soucy \| Mohammadi \| Rosa-Neto \| Pascoal \| Savard \| Kang \| Therriault \| Benali	Soucy
52	PET beta-amyloid deposition in healthy older adults is associated with decreased lure discrimination on a spatial mnemonic similarity task	Webb \| Foster \| Horn \| Kennedy \| Rodrigue	Webb
21	Concordance of visual and quantitative assessments of baseline amyloid scans in the GRADUATE gantenerumab studies	Klein \| Delmar \| Voyle \| Hesterman \| Petrulli \| Ovens \| Baudler \| Fontoura \| Doody \| Kerchner	Klein
54	Tau pathology and relative cerebral blood flow are independently associated with cognition in Alzheimer’s disease	Wolters \| Visser \| Verfaillie \| Coomans \| Timmers \| Tuncel \| Boellaard \| Windhorst \| Scheltens \| van der Flier \| Ossenkoppele \| van Berckel	Wolters
53	Socioeconomic status mediates racial differences seen using the A-T(N) Framework	Wisch \| Hudson \| Coble \| Xiong \| Babulal \| Gordon \| Flores \| Dincer \| Benzinger \| Morris \| Ances	Ances
27	Probability Template Method for Analysis of Down Syndrome Amyloid PET	Laymon \| Minhas \| James \| Christian \| Cohen \| Klunk \| Tudorascu \| Royse \| Zaman \| Handen	Laymon
36	Association between Cerebral Amyloid Accumulation and Synaptic Density in Alzheimer’s Disease: A Multitracer PET Study	O Dell \| Mecca \| Chen \| Godek \| Harris \| Bartlett \| Banks \| Kominek \| Zhao \| Naganawa \| Toyonaga \| Lu \| Nabulsi \| Vander Wyk \| Varma \| Arnsten \| Huang \| Carson \| van Dyck	O'Dell
10	Quantifying off-target skull binding in [18F]Flortaucipir PET studies	Flores \| Gordon \| Su \| Christensen \| Dincer \| Adedokun \| Hornbeck \| Morris \| Benzinger	Flores
40	MIND MAPS: Assessment of the mitochondrial - endoplasmic reticulum - synaptic axis in neurodegeneration by [18F]BCPP-EF, [11C]SA4503 and [11C]UCB-J PET imaging	Rabiner \| Mansur \| Venkataraman \| Price \| Wilson \| Pagano \| Clarke \| Lewis \| Matthews \| Rowe \| Brooks \| Middleton \| Politis \| Rohrer \| Comley \| Evans \| Martarello \| Chen \| Schwarz \| Schmidt \| Tsukada \| Passchier \| Gunn \| Consortium	Rabiner
14	Amyloid binding is associated with markers of white matter microstructure in patients with significant white matter disease	Goubran \| Ozzoude \| Adamo \| Zukotynski \| Bocti \| Borrie \| Chertkow \| Frayne \| Gao \| Hsiung \| Kiss \| Laforce \| Noseworthy \| Prato \| Ramirez \| Sahlas \| Scott \| Smith \| Sossi \| Strother \| Swartz \| Tardif \| Thiel \| Soucy \| Black	Goubran
20	Hippocampal volume mediates the relationship between amyloidosis and amyloid-sensitive cognitive composite in preclinical AD	Kim \| Hahn \| Kim \| Kim \| Chin \| Seo	Hahn
7	Tau pathology and synaptic loss are closely associated in Alzheimer’s disease in vivo: a combined [18F]flortaucipir and [11C]UCB-J PET study	Coomans \| Verfaillie \| Wolters \| Tuncel \| Golla \| Ossenkoppele \| Scheper \| Schober \| Sweeney \| Ryan \| Schuit \| Windhorst \| Scheltens \| Boellaard \| van Berckel	Coomans
5	Early detection of amyloid load using 18F-Florbetaben PET	Bullich \| Roé-Vellvé \| Marquié \| Villemagne \| Sanabria \| Tartari \| Sotolongo \| Doré \| Koglin \| Müller \| Perrotin \| De Santi \| Tárraga \| Stephens \| Rowe \| Seibyl \| Boada	Bullich
8	Longitudinal dynamic [18F]flortaucipir PET reveals increased early stage tau pathology in individuals with subjective cognitive decline	Coomans \| Visser \| Ossenkoppele \| Verfaillie \| Timmers \| Wolters \| Tuncel \| Schmidt \| Boellaard \| Windhorst \| Scheltens \| van der Flier \| van Berckel	Coomans
34	Sex-specific differences in [18F]AV-1451 off-target retention	Minhas \| Yu \| Laymon \| Lopresti \| Snitz \| Tudorascu \| Aizenstein \| Lopez \| Mathis \| Klunk \| Cohen	Minhas
33	MRI and PET data harmonization in a two-site Down syndrome study	Minhas \| Yang \| Muschelli \| Laymon \| Zammit \| Ellison \| Johnson \| Mathis \| Crainiceanu \| Klunk \| Handen \| Christian \| Cohen \| Tudorascu	Tudorascu
28	Visualizing brain astrocytes - characterization of 3H-BU99008 in human AD brain tissue	Lemoine \| Malarte \| Koistinen \| Nordberg	Lemoine
24	Validation of highly sensitive and specific florbetaben positivity thresholds using ADNI participants and young controls	Landau \| Korman \| Bullich \| De Santi \| Stephens \| Koeppe \| Jagust	Landau
51	Association Between [18F]NAV4694 PET Amyloid-β Measures and Fluid Biomarkers Across the Spectrum of Alzheimer Disease	Wang \| Pascoal \| Therriault \| Benedet \| Lussier \| Savard \| Kang \| Tissot \| Gauthier \| Rosa-Neto	Wang
55	Amyloid Load trajectories and chronicity reveal groups of early amyloid accumulators in Down syndrome	Zammit \| Koscik \| Laymon \| Betthauser \| Tudorascu \| Cohen \| Minhas \| Johnson \| Zaman \| Mathis \| Klunk \| Handen \| Christian	Zammit
56	Hippocampal-retrosplenial cortex connectivity predicts tau accumulation in cognitively normal older adults	Ziontz \| Adams \| Baker \| Jagust	Ziontz
42	Linking APOE ε4, blood-brain barrier dysfunction and inflammation to Alzheimer’s pathology	Riphagen \| Ramakers \| Freeze \| Pagen \| Hanseeuw \| Verbeek \| Verhey \| Jacobs	Riphagen
9	Preliminary evaluation of synaptic vesicle protein SV2A imaging with [11C]UCB-J across the cognitive spectrum	DiFilippo \| Murali \| McKinney \| Davenport \| Barnhart \| Engle \| Betthauser \| Johnson \| Bendlin \| Christian	DiFilippo
25	Additive contribution of white matter hyperintensity to amyloid and neurodegeneration on cognitive decline in a diverse, community-based cohort of older adults	Lao \| Chesebro \| Colon \| Igwe \| Gu \| Schupf \| Manly \| Stern \| Mayeux \| Brickman	Lao
6	Age-related neural dedifferentiation of episodic memory networks is related to beta-amyloid and tau pathology in normal aging	Cassady \| Adams \| Maass \| Harrison \| Baker \| Jagust	Cassady
23	Genetically informed quantitative Gradient Recalled Echo MRI reveals brain tissue in hippocampal subfields void of neurons in mild Alzheimer disease	Kothapalli \| Benzinger \| Aschenbrenner \| Goyal \| Fagan \| Raichle \| Morris \| Yablonskiy	Kothapalli
2	Examining regional MK-6240 patterns and associations with amyloid and cognitive decline	Betthauser \| Cody \| Koscik \| Jonaitis \| Erickson \| Converse \| Murali \| Barnhart \| Stone \| Mueller \| Clark \| Asthana \| Christian \| Johnson	Betthauser
50	Neuropsychiatric symptoms in cognitively impaired individuals are correlated with tau deposition	Tissot \| Therriault \| Pascoal \| Chamoun \| Lussier \| Savard \| Mathotaarachchi \| L. Benedet \| Thomas \| Rosa-Neto \| Gauthier	Tissot
38	Amyloid PET variability due to variation in MRI protocol and anatomical segmentation	Palombit \| Manber \| Joules \| Wolz	Manber
48	Monitoring disease pathophysiology using multiparametric PET acquisitions: The McGill TRIAD Cohort	Stevenson \| Chamoun \| A. Pascoal \| L. Benedet \| Kang \| Mathotaarachchi \| Therriault \| Thomas \| Savard \| Tissot \| Lussier \| Vinet-Celluci \| Rahmouni \| Gagné \| Joung \| Sbeiti \| Shin \| Vitali \| Gauthier \| Rosa-Neto	Stevenson
39	The impact of automatic Tau PET processing on uptake variability and power analysis in AD	Palombit \| Manber \| Joules \| Wolz	Manber
32	PiB tracer delivery decreases overtime in preclinical AD – impact for amyloid pathology measurement	Mayblyum \| Becker \| Schultz \| Farrell \| Jacobs \| Rubinstein \| Sanchez \| Thibault \| Sperling \| Price \| Johnson \| Hanseeuw	Mayblyum
15	CSF dynamics explains discrepant PET-CSF AD biomarkers	Gunter \| Senjem \| Cogswell \| Schwarz \| Lowe \| Kantarci \| Vemuri \| Elder \| Botha \| Graff-Radford \| Jones \| Mielke \| Graff-Radford \| Knopman \| Petersen \| Jack, Jr.	Gunter
45	Development of a Qualitative Read Method for Characterizing the Presence and Extent of Brain Tau Deposition Using [18F]MK-6240 PET Imaging	Seibyl \| Salinas \| Rajagovindan \| Hutchison \| Beaver \| Martarello	Seibyl
26	White matter hyperintensities are related to tau burden in late-Braak stage regions	Lao \| Laing \| Igwe \| Chesebro \| Kreisl \| Moreno \| Luchsinger \| Brickman	Lao
44	MCI patients demonstrate reliably increasing 18F-AV1451 PET uptake across three exams	Scott \| Adamczuk \| Gorman \| Runkle \| Suhy	Scott
37	A clinically applicable proxy for gold standard quantification of amyloid-beta in Alzheimer’s disease: Bolus plus constant infusion 18F-AV45 PET	Ottoy \| Kang \| Verhaeghe \| Stroobants \| Bouhachi \| Hsiao \| Stevenson \| Rahmouni \| Chartrand \| Massarweh \| Soucy \| Gauthier \| Rosa-Neto \| Staelens	Ottoy
13	Beta-amyloid deposition and its association with metabolism	Gordon \| Goyal \| Couture \| Flores \| Morris \| Raichle \| Benzinger \| Vlassenko	Gordon
19	Data-Driven Biological Pattern Scoring of Flortaucipir Scans Outperforms ROIs	Jones \| Graff-Radford \| Botha \| Senjem \| Wiste \| Josephs \| Whitwell \| Kantarci \| Boeve \| Petersen \| Knopman \| Lowe \| Jack	Jones
3	Transcriptomic profiling of brain amyloidosis using peripheral blood-based gene expression	Bharthur Sanjay \| Svaldi \| Apostolova	Bharthur Sanjay
35	Polygenic Risk for Cerebrospinal Fluid (CSF) Amyloid Predicts Brain Amyloid in Clinically Normal Older Adults	Moore \| Dumitrescu \| Schultz \| Raghavan \| Johnson \| Mayeux \| Sperling \| Hohman \| Mormino	Moore
31	Age prediction and amyloid deposition in SuperAgers	Martersteck \| Besson \| Sridhar \| Makowski-Woidan \| Parrish \| Katsaggelos \| Mesulam \| Bandt \| Rogalski	Martersteck
22	Regional amyloid burden is associated with higher quantitative T1 in discrete hippocampal sub-regions	Kohli \| Yang \| Vogt \| Asthana \| Betthauser \| Alexander \| Christian \| Johnson \| Kecskemeti \| Bendlin	Kohli
49	Interaction between amyloid and neuroinflammation on apathy along the Alzheimer’s disease spectrum	Tissot \| Kang \| L. Benedet \| Rahmouni \| Pascoal \| Chamoun \| Therriault \| Lussier \| Savard \| Mathotaarachchi \| Thomas \| Gauthier \| Rosa-Neto	Tissot
41	Associations between Neurogranin and imaging biomarkers of Alzheimer’s disease	Rahmouni \| L.Benedet \| Nicholas J. \| Tissot \| Pascoal \| Kvartsberg \| Chamoun \| Kang \| Lussier \| Therriault \| Stevenson \| Savard \| Mathotaarachchi \| Thomas \| Gauthier \| Zetterberg \| Blennow \| Rosa-Neto	Rahmouni
43	Heterogeneity of tau PET signal in the sub-nuclei of the amygdala	Rubinstein \| Jacobs \| Augustinack \| Properzi \| Becker \| Mayblyum \| Thibault \| Sanchez \| Schultz \| Hanseeuw \| Gomez-Isla \| Lois-Gomez \| Price \| Sperling \| Johnson	Rubinstein
18	Retrospective prediction of amyloid accumulation trajectories in a risk-enriched Alzheimer’s disease cohort with sequential neural network	Hwang \| Koscik \| Betthauser \| Tao \| Kim \| Johnson \| Singh	Hwang
16	Predicting future amyloid spread with machine learning using longitudinal [C11]PiB-PET in preclinical Alzheimer's disease	Hao \| Vogt \| Meng \| Hwang \| Koscik \| Betthauser \| Christian \| Johnson \| Bendlin \| Singh	Singh
30	Phantom-based harmonization of PET image reconstruction parameters between the Siemens ECAT HR+ PET and the GE Discovery MI PET/CT scanners	Lois \| Grogg \| El Fakri \| Johnson \| Price	Lois

POSTER SESSIONS: 2A - Thursday, January 16 - 10:45 - 11:30 am; 2B - Thursday, January 16, 4:00 - 4:45 pm

BOARD	Title	Author Name	Presenter
100	Entorhinal tau pathology is associated with medial temporal lobe hyperactivity in aging	Adams \| Maass \| Berron \| Harrison \| Baker \| Thomas \| Stanfill \| Jagust	Adams
80	Sex differences in the rates of cognitive decline associated with temporal lobe FTP-PET signal: findings from the Harvard Aging Brain Study	Buckley \| Properzi \| Schultz \| Jacobs \| Kirn \| Rentz \| Hanseeuw \| Johnson \| Sperling	Buckley
73	Imaging synaptic and mitochondrial function in frontotemporal dementia using [11C]UCB-J, [18F]BCPP-EF and [11C]SA4503 PET	Clarke \| Mansur \| Passchier \| Lewis \| Evans \| Chen \| Schwarz \| Takano \| Gunn \| Cash \| Rabiner \| Rohrer	Clarke
105	Longitudinal associations between lifestyle risk, β-amyloid, and cognition in late-midlife	Cody \| Koscik \| Birdsill \| Berman \| Erickson \| Chin \| Clark \| Christian \| Betthauser \| Johnson	Cody
62	Correlation of QSM signal with Alzheimer’s disease biomarkers	Cogswell \| Wiste \| Senjem \| Therneau \| Lowe \| Knopman \| Botha \| Graff-Radford \| Jones \| Kantarci \| Vemuri \| Ferman \| Boeve \| Mielke \| Schwarz \| Gunter \| Petersen \| Jack	Cogswell
71	Quantitative regional amyloid burden and white matter changes in preclinical Alzheimer’s Disease	Collij \| Top \| Stickney \| Ingala \| Tomassen \| Lopes Alves \| Yaqub \| Wink \| Van 't Ent \| Scheltens \| Van Berckel \| Visser \| Barkhof \| Den Braber \| AMYPAD consortium	Collij
70	Individual variability in the cortical distribution of elevated 18F-AV1451 and 11C-PIB in a heterogeneous sample of AD patients	Collins \| Eckbo \| McGinnis \| Dickerson	Collins
93	Neuroinflammation in Alzheimer’s disease patients and correlates with amyloid and tau deposition	Edison \| Leng \| Dani \| Brooks	Edison
85	Sex differences in regional tau deposition in cognitively impaired patients with Alzheimer’s disease	Edwards \| La Joie \| Iaccarino \| Kim \| Baker \| Casaletto \| Miller \| Jagust \| Rabinovici	Edwards
69	Higher microglia biomarker levels are associated with slower rates of amyloid-beta accumulation in humans and in a transgenic mouse model of amyloid-beta	Ewers \| Brendel \| Suarez-Calvet \| Biechele \| Sacher \| Blume \| Haass \| Franzmeier	Ewers
99	Early declines in learning and executive function associated with accumulating Aβ not tau in low PIB adults	Farrell \| Papp \| Buckley \| Jacobs \| Schultz \| Properzi \| Hanseeuw \| Rentz \| Johnson \| Sperling	Farrell
68	Association of tau tangle burden with depressive symptoms in community dwelling older adults: a longitudinal study	Gatchel \| Marshall \| Yang \| Donovan \| Buckley \| Properzi \| Quiroz \| Rabin \| Vannini \| Amariglio \| Chhatwal \| Rentz \| Blacker \| Sperling \| Johnson \| Hanseeuw	Gatchel
78	Amyloid deposition affects the topography of cortical thinning in Lewy Body Disease	Ye \| Touroutoglou \| Brickhouse \| Katz \| Growdon \| Johnson \| Dickerson \| Gomperts	Gomperts
107	Data-driven approach to characterization of tau accumulation in Braak staging groups	Groh \| Svaldi \| Stage \| Sanjay \| Risacher \| Saykin \| Apostolova	Groh
77	A sensitive composite model to determine subtle cognitive differences in preclinical Alzheimer’s disease	Hahn \| Kim \| Kim \| Jang \| Kim \| Na \| Chin \| Seo	Hahn
61	Defining a Centiloid scale threshold predicting long-term progression to dementia in patients attending the Memory Clinic: an F18-Flutemetamol amyloid-PET study	Hanseeuw \| Malotaux \| Dricot \| Quenon \| Cerman \| Buckley \| Farrar \| Ivanoiu \| Lhommel	Hanseeuw
92	Amyloid deposition disrupts functional connectivity and graph properties within the Default Mode Network	Ingala \| Wink \| Prent \| van 't Ent \| Tomassen \| ten Kate \| Konijnenberg \| Collij \| Yaqub \| Scheltens \| de Goes \| Teunissen \| Barkhof \| van Berckel \| Visser \| den Braber	den Braber
74	First-in-human evaluations of [11C]PS13 for imaging COX-1 and [11C]MC1 for imaging COX-2	Kim \| Juarez Anaya \| Lee \| Hong \| Miller \| Telu \| Morse \| Singh \| Cortes-Salva \| Henry \| Ruiz-Perdomo \| Montero Santamaria \| Liow \| Zoghbi \| Fujita \| Katz \| Pike \| Innis	Kim
91	Prevalence of amyloid PET positivity in cognitively normal the East Asian populations	Kim \| Jung \| Na \| Kim \| Won \| Seo	Kim
64	Evaluating the relationships among odor identification, tau pathology and neuroinflammation in Alzheimer’s disease	Klein \| Yan \| Johnson \| Tomljanovic \| Zou \| Polly \| Honig \| Brickman \| Stern \| Lee \| Kreisl	Klein
67	Distinct effects of APOE ε2 on Aβ in Alzheimer- and Vascular-type cognitive impairment	Lee \| Lee \| Park \| Choe \| Park \| Cheon \| Hahn \| Ossenkoppele \| Kim \| Kim \| Yoo \| Jang \| Cho \| Kim \| Kim \| Jung \| Park \| DeCarli \| Weiner \| Yun \| Na \| Seo	Lee
79	Longitudinal change in amyloid load over a 5-year period in cognitively healthy APOE4 carriers versus non-carriers: Effect of reference region	Luckett \| Adamczuk \| Schaeverbeke \| Gabel \| Van Laere \| Dupont \| Vandenberghe	Luckett
113	Mild behavioral impairment is associated with tau pathology in cognitively impaired elderly individuals	Lussier \| Pascoal \| Therriault \| Tissot \| Savard \| Benedet \| Mathotaarachchi \| Stevenson \| Ismail \| Rosa-Neto \| Gauthier	Lussier
114	Modeling the trajectory of tau deposition in autosomal-dominant Alzheimer’s disease using the high-affinity tau tracer [18F]MK6240	Lussier \| Therriault \| Pascoal \| Savard \| Mathotaarachchi \| Robb \| Stevenson \| Gauthier \| Rosa-Neto	Lussier
101	Clinicopathological confirmation of 123I-FP-CIT SPECT (ioflupane) quantification methods in a spectrum of neurodegenerative syndromes and associated pathologies	Maltais \| Jordan \| Miyagawa \| Lesnick \| Przybelski \| Min \| Dickson \| Murray \| Kantarci \| Boeve \| Lowe	Maltais
106	Exploring relationships between tau burden and naming in the aphasic variant of Alzheimer’s disease	Martersteck \| Sridhar \| Coventry \| Eldes \| Wood \| Kim \| Mesulam \| Rogalski	Martersteck
65	Elevated soluble phosphorylated tau is a marker of early amyloid PiB PET abnormalities and accumulation	McDade \| Li \| Joseph-Mathurin \| Benzinger \| Fagan \| Xiong \| Barthélemy \| Bateman	McDade
112	A clinically-relevant scheme for qualitatively rating tau PET, amyloid PET, and MRI in neurodegenerative cognitive presentations	McGinnis \| Collins \| Eckbo \| Brickhouse \| Dickerson	McGinnis
66	Cerebrospinal fluid and PET measures of tau pathology may indicate different stages of AD pathological progression	Meyer \| Pichet Binette \| Gonneaud \| Breitner \| Villeneuve	Meyer
96	Use of the plasma amyloid-beta 42/40 ratio for predicting amyloid PET in a community-based population	Mielke \| Algeciras-Schimnich \| Campbell \| Syrjanen \| Knopman \| Jack Jr. \| Peterson	Mielke
111	Cerebrospinal fluid matrix metalloproteinases are associated with compromised white matter microstructure among older adults: the Vanderbilt memory & aging project	Moore \| Pechman \| Acosta \| Bell \| Anderson \| Landman \| Blennow \| Zetterberg \| Gifford \| Hohman \| Jefferson	Moore
94	Development of new alpha7 nicotinic receptor ASEM analogs for PET imaging	Nordberg \| Lemoine \| Mohan \| Kuang \| Nag \| Jia \| Miranda Azpiazu \| Datta \| Arakawa \| Varnäs \| Ågren \| Långström \| Halldin	Nordberg
108	Associations between Alzheimer’s disease biomarkers and cognition among cognitively normal older adults	Oh \| Correia \| Salloway	Oh
75	[11C]MK-6884 PET tracer for M4 muscarinic cholinergic receptors in Alzheimer’s disease: comparison with [18F]FDG PET	Pascual \| Zanotti-Fregonara \| Yu \| Funk \| Arbones \| Wang \| Li \| Cheng \| Anderson \| Hostetler \| Basile \| Masdeu	Pascual
81	Amyloid and tau PET burden are associated with white matter bundle abnormalities in asymptomatic individuals at risk of Alzheimer’s disease	Pichet Binette \| Theaud \| Gonneaud \| Poirier \| Descoteaux \| Villeneuve	Pichet Binette
104	Increased risk of Alzheimer’s disease in alcohol use disorder is not mediated by amyloid-beta in a middle-aged cross-sectional cohort	Royse \| Himes \| Minhas \| Lopresti \| Flanigan \| Narendran	Royse
86	Cross-sectional and longitudinal non-dichotomized CSF/PET Aβ data support existence of “CSF+ first” vs. “PET+ first” pathways of Aβ biomarkers changes	Sala \| Nordberg \| Rodriguez-Vieitez	Sala
82	NeuroToolkit CSF biomarkers track the progression of Alzheimer’s disease at very early stages and show that inflammatory markers modulate cerebral amyloid accumulation	Salvadó \| Molinuevo \| Milà-Alomà \| Blennow \| Zetterberg \| Operto \| Falcón \| Batrla \| Battle \| Buckley \| Farrar \| Minguillon \| Fauria \| Sánchez-Benavides \| Suárez-Calvet \| Gispert \| the ALFA study	Salvadó
83	T1rho MRI measurement of amyloid plaque burden in cognitively unimpaired individuals: preliminary results in the ALFA+ cohort	Falcón \| Montesinos \| Grau-Rivera \| Suárez-Calvet \| Puig-Pijoan \| Cascales \| Navalpotro-Gomez \| Fernández-Lebrero \| Sánchez-Valle \| Gelpi \| Sanfeliu \| Rojas \| Perissinotti \| Niñerola-Baizán \| Salvadó \| Minguillon \| Fauria \| Molinuevo \| Sánchez-González \| Gispert \| the ALFA study	Salvadó
84	Preliminary quantitative results of the AMYPAD prognostic and Natural History Study	Gispert \| Lopes-Alves \| Gray \| Buckley \| Collij \| Heeman \| Salvadó \| Scheltens \| Frisoni \| Ritchie \| Vellas \| Stephens \| Ford \| Molinuevo \| Farrar \| Barkhof \| the AMYPAD Consortium	Salvadó
72	Effect of genetic risk, brain amyloid and hippocampal volume on normal variation in episodic memory performance in middle-aged and older adults	Schaeverbeke \| Gabel \| Adamczuk \| Van Laere \| Dupont \| Vandenberghe	Schaeverbeke
103	White matter disruption is an early and progressive feature of pre-symptomatic Dutch-type hereditary cerebral amyloid angiopathy	Scott \| Schultz \| Sohrabi \| Gardener \| Taddei \| Bateman \| Benzinger \| Johnson \| Sperling \| Martins \| Greenberg \| Chhatwal \| Investigators	Scott
88	Head-to-head comparison of F-Florbetaben and F-Flutemetamol uptakes in the cortex, striatum and white matter	Seo \| Cho \| Moon \| Choe \| Na	Seo
90	PI-2620 Tau PET is associated with amyloid-beta levels in scans from subjects of the elenbecestat MissionAD program	Stephens \| Bullich \| Mueller \| Berndt \| De Santi \| Scott \| Adamczuk \| Suhy \| Kaplow \| Giroux \| Krause \| Chang \| Albala	Stephens
110	Using famous faces to investigate the neural systems involved in name retrieval	Tennant \| Jagust \| La Joie \| Adams \| Winer	Tennant
109	In vivo association of mitochondrial dysfunction with tau pathology in early Alzheimer’s disease	Terada \| Therriault \| Min Su \| Savard \| Ouchi \| Rosa-Neto	Terada
102	Preliminary results: PiB and MK6240 regional PET measures associated with digitized clock drawing performance	Mayblyum \| Thibault \| Moody \| Farrell \| Jiang \| Jacobs \| Rubinstein \| Sanchez \| Katz \| Sperling \| Papp \| Rentz \| Johnson	Thibault
97	Associations between longitudinal cognitive measures and cross-sectional tau in adults with Down syndrome	Tudorascu \| Comer \| Zammit \| Laymon \| Minhas \| Ellison \| Zaman \| Ances \| Johnson \| Mathis \| Klunk \| Christian \| Handen \| Hartley \| Cohen	Tudorascu
60	Longitudinal flortaucipir ([18F]AV-1451) PET uptake in Semantic Dementia	Utianski \| Whitwell \| Martin \| Botha \| Schwarz \| Duffy \| Clark \| Spychalla \| Senjem \| Petersen \| Knopman \| Jack, Jr. \| Lowe \| Josephs	Utianski
76	Assessing Aβ, tau, and reactive astrocytosis in aging and AD	Villemagne \| Harada \| Doré \| Furumoto \| Mulligan \| Kudo \| Krishnadas \| Huang \| Yanai \| Rowe \| Okamura	Villemagne
63	Developing a novel alpha-synuclein (a-syn) positron emission tomography (PET) tracer for the diagnosis of Parkinson’s disease (PD) and other a-synucleinopathies	Vokali \| Molette \| Tsika \| Ravache \| Rodriguez \| Jürgens \| Melo dos Santos \| Sandiego \| Russell \| Gunn \| Darmency \| Piorkowska \| Poli \| Kroth \| Capotosti \| Hliva \| Sol \| Marek \| Stöhr \| Lowe \| Pfeifer \| Kosco-Vilbois	Vokali
95	Biological underpinnings of typical and atypical Alzheimer’s dementia phenotypes	Whitwell \| Tosakulwong \| Graff-Radford \| Weigand \| Schwarz \| Senjem \| Ertekin-Taner \| Jones \| Boeve \| Knopman \| Jack \| Petersen \| Lowe \| Josephs	Whitwell
89	Sleep impairment predicts longitudinal accumulation of β-amyloid	Winer \| Mander \| Jagust \| Walker	Winer
87	Personality and amyloid accumulation in cognitively normal aging	Yoon \| Baker \| Korman \| Tennant \| Harrison \| Jagust	Yoon
98	Associations of amyloid deposition and FDG uptake in aging and cognitively impaired elders with and without moderate to severe periventricular white matter hyperintensities	Zukotynski \| Gaudet \| Kuo \| Adamo \| Goubran \| Scott \| Bocti \| Borrie \| Chertkow \| Frayne \| Hsiung \| Laforce \| Noseworthy \| Prato \| Sahlas \| Smith \| Sossi \| Thiel \| Soucy \| Tardif \| Black	Zukotynski

POSTER SESSIONS: 3A - Friday, January 17, 9:15 - 10:00 am; 3B - Friday, January 17, 3:15 - 4:00 pm

BOARD	Title	Author Name	Presenter
132	CSF P-tau detects cerebral tau accumulation earlier than tau PET in amyloid positive elderly adults	Guo \| Jagust \| Landau	Guo
162	Association between cerebrospinal fluid neurofilament light chain and markers of neurofibrillary pathophysiology: Findings from the Knight Alzheimer Disease Research Center	Schultz \| Schindler \| Chen \| Sutphen \| Morris \| Fagan \| Gordon \| Benzinger	Schultz
130	Functional connectivity brain architecture predicts the rate of tau accumulation in Alzheimer’s disease	Franzmeier \| Neitzel \| Rubinski \| Smith \| Strandberg \| Ossenkoppele \| Hansson \| Ewers	Franzmeier
154	Widespread amyloid is necessary to detect tau-PET signal beyond the entorhinal cortex and cognitive decline	Ozlen \| Binette \| Köbe \| Meyer \| Villeneuve	Ozlen
135	Preclinical characterization of [18F]THK-5562, a novel tau PET tracer with little off-target binding	Harada \| Lerdsirisuk \| Yiqing \| Ezura \| Shimizu \| Morito \| Arai \| Yanai \| Kudo \| Furumoto \| Okamura	Harada
155	Using 18F-Flortaucipir visual assessment to define T-status in the AT(N) framework: evaluation of intra- and inter-rater reliability	Provost \| Iaccarino \| Soleimani-Meigooni \| Lesman-Segev \| La Joie \| Edwards \| Strom \| Pham \| Mellinger \| Janabi \| Baker \| Jagust \| Rabinovici	Provost
156	Defining T-status in the AT(N) framework: comparison of 18F-Flortaucipir visual assessment, SUVR quantification and CSF pTau	Provost \| Iaccarino \| Soleimani-Meigooni \| Lesman-Segev \| La Joie \| Mattsson \| Hansson \| Eichenlaub \| Edwards \| Strom \| Pham \| Mellinger \| Janabi \| Baker \| Jagust \| Rabinovici	Provost
133	Amyloid, tau, and atrophy in preclinical Alzheimer’s disease: a longitudinal study	Hanseeuw \| Jacobs \| Schultz \| Buckley \| Properzi \| Farrell \| Scott \| Hampton \| Sanchez \| Sperling \| Johnson	Hanseeuw
126	Quantifying tau PET imaging reliably in the presence of off-target binding	Chen \| Gordon \| McCullough \| Zaza \| Mejias \| Dincer \| Flores \| Keefe \| Paulick \| Jackson \| Koudelis \| Su \| Morris \| Benzinger	Chen
157	Plasma neurofilament light is associated with regional tau tangle burden in autosomal dominant Alzheimer's disease: findings from the COLBOS Project	Quiroz \| Zetterberg \| Reiman \| Sanchez \| Guzman-Velez \| Fox-Fuller \| Arboleda-Velasquez \| Baena \| Gatchel \| Sperling \| Johnson \| Blennow \| Lopera	Quiroz
159	Measuring increases of tau pathology in Alzheimer's disease using [18F]GTP1 (Genentech tau probe 1) PET imaging	Sanabria Bohorquez \| Baker \| Manser \| Toth \| Teng \| Marik \| Weimer	Sanabria Bohorquez
131	How innocent is PART? Mesial temporal tau is associated with worse cognitive performance in Aβ-negative cognitively normal individuals	Groot	Groot
137	In vivo amyloid-PET and tau-PET evidence in early-onset Alzheimer’s Disease: taking the LEADS	Iaccarino \| La Joie \| Lesman-Segev \| Soleimani-Meigooni \| Provost \| Collins \| Aisen \| Borowski \| Eloyan \| Fagan \| Foroud \| Gatsonis \| Jack Jr. \| Kramer \| Saykin \| Toga \| Vemuri \| Day \| Graff-Radford \| Honig \| Jones \| Masdeu \| Mendez \| Onyike \| Rogalski \| Salloway \| Wolk \| Wingo \| Koeppe \| Dickerson \| Apostolova \| Carrillo \| Rabinovici	Iaccarino
174	Associations of tau pathology and functional connectivity with retrospective cognitive change among cognitively normal older adults	Shafer \| Bilgel \| Ziontz \| Wong \| Resnick	Ziontz
158	Application of tau PET as a biomarker of Alzheimer’s disease in therapeutic trials: a pharmaceutical industry perspective	Salinas \| Lohith \| Guo \| Wooten \| Tulip \| Sanjeewa \| Comley \| Sur \| Hostetler \| Beaver \| Martarello	Salinas
167	Intrinsic connectivity of the human brain provides scaffold for tau aggregation in Alzheimer's disease	Therriault \| Pascoal \| Savard \| Mathotaarachchi \| Benedet \| Chamoun \| Gauthier \| Saha-Chaudhuri \| Massarweh \| Rosa-Neto	Therriault
138	Multimodal in vivo investigation of amyloid and tau biomarkers associations with cerebrospinal fluid NfL and YKL40 levels	Iaccarino \| La Joie \| Edwards \| Lesman-Segev \| Strom \| Pham \| Chaudhary \| Fenton \| Jerome \| Janabi \| Baker \| Miller \| Jagust \| Fagan \| Rabinovici	Iaccarino
122	Perfusion-phase 18F-PI-2620 tau-PET imaging as a surrogate marker of neuronal injury	Brendel \| Beyer \| Nitschmann \| Barthel \| van Eimeren \| Marek \| Song \| Palleis \| Respondek \| Sauerbeck \| Hammes \| Barbe \| Onur \| Jessen \| Saur \| Schroeter \| Rumpf \| Rullmann \| Schildan \| Patt \| Neumaier \| Barret \| Madonia \| Russel \| Stephens \| Roeber \| Herms \| Bötzel \| Levin \| Classen \| Hoeglinger \| Bartenstein \| Villemagne \| Drzezga \| Seibyl \| Sabri	Brendel
123	Binding characteristics of 18F-PI-2620 differentiate the clinically predicted tau isoform in suspected 3/4-repeat and 4-repeat tauopathies	Brendel \| Song \| Beyer \| Barthel \| van Eimeren \| Marek \| Palleis \| Kaiser \| Respondek \| Sauerbeck \| Hammes \| Barbe \| Onur \| Jessen \| Saur \| Schroeter \| Rumpf \| Rullmann \| Schildan \| Patt \| Neumaier \| Barret \| Madonia \| Russel \| Stephens \| Roeber \| Herms \| Bötzel \| Levin \| Classen \| Hoeglinger \| Bartenstein \| Villemagne \| Drzezga \| Seibyl \| Sabri	Brendel
124	18F-PI2620 tau-PET for assessment of heterogeneous neuropathology in corticobasal syndrome	Brendel \| Palleis \| Prix \| Gehmeyr \| Bötzel \| Danek \| Höllerhage \| Sauerbeck \| Beyer \| Nitschmann \| Song \| Stephens \| Barthel \| Patt \| Sabri \| Drzezga \| van Eimeren \| Villemagne \| Bartenstein \| Perneczky \| Haass \| Levin \| Hoeglinger	Brendel
173	[18F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer’s disease	Wolters \| Ossenkoppele \| Verfaillie \| Coomans \| Timmers \| Visser \| Tuncel \| Golla \| Windhorst \| Boellaard \| van der Flier \| Teunissen \| Scheltens \| van Berckel	Wolters
170	Hippocampal tau accumulation predicts individual differences in episodic memory in cognitively normal older adults	Trelle \| Toueg \| Castillo \| Channappa \| Corso \| Hunt \| Jayakumar \| Nadiadwala \| Guo \| Azevedo \| Shin \| Davidson \| Deutsch \| Hall \| Sha \| Fredericks \| Kerchner \| Carr \| Chin \| Wagner \| Mormino	Trelle
128	Comparison of quantitative cutoff methods for [18F]AV-1451	Minhas \| Laymon \| Lopresti \| Snitz \| Tudorascu \| Aizenstein \| Lopez \| Mathis \| Klunk \| Cohen	Cohen
134	Increased levels and phosphorylation of soluble tau proteins occur earlier than changes in Tau PET in Alzheimer’s disease	Hansson \| Andersson \| Janelidze \| Ossenkoppele \| Insel \| Strandberg \| Zetterberg \| Blennow \| Chai \| Dage \| Stomrud \| Smith \| Palmqvist \| Mattsson	Hansson
172	Temporal evaluation for maximum CSF pTau181 – [18F]Flortaucipir concordance	Wisch \| Gordon \| Schindler \| Flores \| Dincer \| Fagan \| Benzinger \| Morris \| Ances	Ances
121	Local associations between tau and neurodegeneration among non-demented older adults	Bilgel \| Wong \| Resnick	Bilgel
150	Entorhinal cortical tau accumulation is inversely associated with hippocampal synaptic density in older individuals with normal cognition and early Alzheimer’s disease	Mecca \| Chen \| Naganawa \| Toyonaga \| Godek \| Harris \| Bartlett \| Zhao \| Gallezot \| Nabulsi \| Huang \| Arnsten \| Carson \| van Dyck	Mecca
142	Comparison of longitudinal change metrics for 18F-RO948 PET among cognitively unimpaired and patients with MCI or AD dementia in the BioFINDER2 study	Klein \| Sanabria \| Leuzy \| Borroni \| Mattsson \| Palmqvist \| Stomrud \| Smith \| Hansson	Klein
171	Temporo-limbic tau burden, as measured by 18F-AV1451, is a correlate of hippocampal volume loss over time	Fischer \| Ahnen \| Dissertori \| Lustermann \| Weber \| Buck \| Kagerer \| Gietl \| Hock \| Unschuld	Unschuld
127	[18F]THK5317 imaging as a predictive tool of prospective cognitive decline in prodromal and dementia-stage Alzheimer’s disease	Chiotis \| Savitcheva \| Poulakis \| Saint-Aubert \| Wall \| Antoni \| Nordberg	Chiotis
143	Validation of clinical protocols for clinicians analyzing 18F-PI-2620 tau PET/MRI images	Koran \| Shams \| Adams \| Cazevedo \| Toueg \| Corso \| Hunt \| Castillo \| Hall \| Sha \| Fredericks \| Greicius \| Wagner \| Zaharchuk \| Davidzon \| Chin \| Mormino	Mormino
147	A comparison of ischemic stroke-induced changes on 18F-APN-1607 (18F-PMPBB3) and 18F-THK-5351 uptake patterns	Lin \| Hsiao \| Huang \| Huang	Lin
161	Clinical evaluation o[18F]-JNJ-64326067, a candidate PET tracer for the detection of tau pathology in Alzheimer’s disease	Schmidt \| Janssens \| Moechars \| Rombouts \| Timmers \| Barret \| Constantinescu \| Madonia \| Russell \| Sandiego \| Kolb	Schmidt
141	Prediction of brain tau accumulation in amyloid positive cognitive impairment patients using multimodal biomarkers with machine learning approach	Kim \| Park \| Park \| Kang \| Kim \| Jang \| Kim \| Na \| Lee \| Seo	Kim
125	Optimal reference region for the quantification of tau load in the brain using 18F-PI-2620 PET	Bullich \| Müller \| Roé-Vellvé \| Jovalekic \| Perrotin \| De Santi \| Koglin \| Stephens	Bullich Roig
153	Factors predicting tau PET status in cognitively unimpaired and impaired individuals	Ossenkoppele \| Leuzy \| Cho \| La Joie \| Strandberg \| Matsson \| Palmqvist \| Lyoo \| Rabinovici \| Smith \| Hansson	Ossenkoppele
164	The rate of accumulation of tau aggregates is higher in females and younger individuals	Smith \| Mattsson \| Pontecorvo \| Devous \| Strandberg \| Ossenkoppele \| Hansson	Smith
120	Depression is predicted by tau imaging biomarker among cognitively normal adults	Babulal \| Roe \| Stout \| Rajasekar \| Wisch \| Benzinger \| Morris \| Ances	Ances
169	Elevated medial temporal lobe Tau PET with 18F-PI2620 in normal controls with “borderline” neuropsychological testing profiles	Toueg \| Deutsch \| Castillo \| Hunt \| Corso \| Trelle \| Harrison \| Azevedo \| Shen \| Anders \| Hall \| Fredericks \| Sha \| Davidzon \| Chin \| Khalighi \| Wagner \| Mormino	Toueg
149	18F-APN-1607: a promising PET tracer for multiple tauopathies	Margolin \| Lin \| Tempest \| Chen \| Marek \| Russell \| Sandiego \| Huang \| Hsiao \| Tamagnan \| Alagille \| Guan \| Lu \| Zuo \| Higuchi \| Jang	Margolin
148	Longitudinal change in [18F]GTP1 SUVR over 18 months depends on baseline SUVR intensity and spatial distribution and shows trends with cognitive decline	Manser \| Sanabria Bohorquez \| Teng \| Baker \| Toth \| Marik \| Weimer	Manser
168	Changes in volumetric MRI measures at 12 months significantly correlate with baseline [18F]GTP1 SUVR, but not [18F]GTP1 change	Toth \| Sanabria Bohorquez \| Manser \| Baker \| Teng \| Marik \| Weimer	Toth
163	18F-PM-PBB3 (18F-APN-1607) uptake associates with plasma NfL level and motor disability in patients with progressive supranuclear palsy	Shimada \| Tagai \| Tatebe \| Matsuoka \| Kubota \| Takahata \| Takado \| Shinotoh \| Yamamoto \| Sano \| Seki \| Nakano \| Ono \| Hirano \| Tempest \| Jang \| Sahara \| Kawamura \| Zhang \| Tokuda \| Higuchi	Shimada
136	Comparison of tau PET imaging using 18F-APN-1607 and 18F-THK5351 in Alzheimer's disease patients and normal controls	Hsiao \| Lin \| Huang \| Huang	Hsiao
145	Diagnostic performance of [18F]RO948 tau positron emission tomography in the differentiation of AD from other neurodegenerative disorders	Leuzy \| Smith \| Ossenkoppele \| Santillo \| Borroni \| Klein \| Olsson \| Jögi \| Palmqvist \| Mattsson \| Strandberg \| Stomrud \| Hansson	Leuzy
146	Longitudinal changes in tau pathology measured by [18F]RO948 tau-PET are associated with elevated CSF P-tau: Preliminary findings from the Swedish BioFINDER-2 study	Leuzy \| Klein \| Ossenkoppele \| Mattsson \| Janelidze \| Palmqvist \| Strandberg \| Coloma \| Borroni \| Stomrud \| Smith \| Hansson	Leuzy
166	Tau positivity: comparing flortaucipir meta-ROI vs maximal single region	Therneau \| Schwarz \| Wiste \| Gunter \| Senjem \| Lowe \| Kantarci \| Petersen \| Knopman \| Mielke \| Jones \| Jack	Therneau
165	Resting state functional connectivity associations with F18-Florbetapir PET versus F18-Flortaucipir PET	Svaldi \| Goñi \| Stage \| Abbas \| Dzemidzic \| West \| Risacher \| Saykin \| Apostolova	Svaldi
139	Activated microglia and amyloid load potentiate tau deposition leading to cognitive dysfunction in Alzheimer’s disease	Kang \| Ottoy \| Savard \| Pascoal \| Mathotaarachchi \| Benedet \| Chamoun \| Therriault \| Lussier \| Tissot \| Thomas \| Stevenson \| Rahmouni \| Arias \| Wang \| Massarweh \| Soucy \| Gauthier \| Rosa-Neto	Kang
140	Tauopathy in females is more vulnerable to amyloid or neuroinflammation in Alzheimer’s disease	Kang \| Ottoy \| Chamoun \| Mathotaarachchi \| Savard \| Benedet \| Pascoal \| Therriault \| Lussier \| Tissot \| Thomas \| Stevenson \| Rahmouni \| Fernandez-Arias \| Wang \| Massarweh \| Soucy \| Gauthier \| Rosa-Neto	Kang
152	In vivo uptake of 18F-PM-PBB3 (18F-APN-1607) in patients with corticobasal syndrome	Nakano \| Shimada \| Tagai \| Matsuoka \| Kubota \| Takahata \| Takado \| Shinotoh \| Yamamoto \| Sano \| Seki \| Hirano \| Ono \| Tempest \| Jang \| Sahara \| Kawamura \| Zhang \| Kuwabara \| Higuchi	Nakano
144	Cerebrospinal fluid tau phosphorylated at amino acid 181 or 231: a biomarker comparison in the detection of neurofibrillary tangle pathology in the Alzheimer’s disease spectrum	Benedet \| Ashton \| Pascoal \| Stoops \| Francois \| Vanmechelen \| Karikari \| Mathotaarachchi \| Savard \| Therriault \| Chamoun \| Zetterberg \| Blennow \| Rosa-Neto	Benedet
151	Mental and physical activity during the uptake period affects off-target binding in extra- and within-brain Tau PET (18F-FTP)	Min \| Apgar \| Scott \| Hol \| Lundt \| Albertson \| Schwarz \| Botha \| Vemuri \| Gunter \| Petersen \| Jack \| Lowe	Min
160	Evaluation of tau PET staging in the A4/LEARN Study	Sanchez \| Becker \| Jacobs \| Hanseeuw \| Mayblyum \| Rubinstein \| Thibault \| Schultz \| Seshadri \| Quiroz \| Rentz \| Price \| Sperling \| Johnson \| the A4 Study Team	Sanchez
129	Pilot study on the relationship between 18F-MK-6240 and VBM in early and late stages of AD	Fernandez Arias \| Pascoal \| Benedet \| Thierrault \| Su Kang \| Savard \| Ottoy \| Mathotaarachchi \| Lussier \| Tissot \| Thomas \| Stevenson \| Rahmouni \| Wang \| Massarweh \| Soucy \| Gauthier \| Rosa-Neto	Fernandez Arias