HUMAN AMYLOID IMAGING CONFERENCE

The 15th edition of the HAI was held in Miami, FL on January 11-13, 2023.

HAI 2023 POSTER SESSIONS

Click the “+” to open each module; tables can be sorted by clicking on each item of the header row (board number, poster title, authors and presenter, respectively). Additionally, each table is searchable (use the search field located at the top right of each module).

Please note that we reserve the right to re-arrange the poster allocation.

POSTER SESSIONS: 1A - Wednesday, January 11 - 9:45 - 10:30 am; 1B - Wednesday, January 11, 4:00 - 4:45 pm

Board #	Title	Authors	Presenter	Presenter/Affiliation
1	Effects of de-facing PET and MRI scans on clinical correlations analyses	Schwarz \| Kremers \| Weigand \| Prakaashana \| Senjem \| Lowe \| Gunter \| Kantarci \| Vemuri \| Petersen \| Knopman \| Jack	Schwarz, Christopher	Christopher Schwarz, Mayo Clinic, Rochester, MN, US
2	Non-invasive quantification and SUVR validation of [18F]-florbetaben with total-body EXPLORER PET	Holy \| Alfaro \| Fletcher \| Bhattarai \| Spencer \| Cherry \| DeCarli \| Fan	Holy, Emily	Emily Holy, Department of Neurology, UC Davis Health, Davis, CA, US
3	PET imaging probe development for aggregated alpha-synuclein	Gomperts \| Liu \| Bai \| Xu \| Rose \| Celikag \| Ndayisaba \| Khurana \| Bartels \| Wang	Gomperts, Stephen	Stephen Gomperts, Department of Neurology, Massachusetts General Hospital, Boston, MA, US
4	Cross-modality transformer for low-dose tau PET imaging	Jang \| Lois \| Becker \| Thibault \| Price \| Johnson \| El Fakhri \| Gong	Gong, Kuang	Kuang Gong, Gordon Center for Medical Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA, US
5	Tau PET positivity reveals Alzheimers disease related fast cognitive decline	Ioannou \| Bucci \| Nordberg \| Chiotis	Ioannou, Konstantinos	Konstantinos Ioannou, Nordberg Translational Molecular Imaging Lab, Division of Clinical Geriatrics, Center for Alzheimers Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, SE
6	Positive 18F-APN-1607 tau PET imaging findings in patients with Progressive Supranuclear Palsy-like extrapyramidal symptoms caused by TBK1 mutations	Liu \| Lu \| Sun \| Li \| Yen \| Jang \| Zuo \| Wang	Liu, Feng-Tao	Feng-Tao Liu, Department of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, CN
7	In vivo visualization of tau deposits in corticobasal syndrome by 18F-Florzolotau PET	Liu \| Lu \| Li \| Jiao \| Chen \| Yao \| Liang \| Ge \| Li \| Shen \| Wu \| Sun \| Wu \| Yen \| Zuo \| Wang	Liu, Feng-Tao	Feng-Tao Liu, Department of Neurology, National Research Center for Aging and Medicine, National Center for Neurological Disorders, and State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, CN
8	Imaging neuroinflammation with astrocyte-PET and bio-fluid biomarkers in patients with cognitive impairment	Chiotis \| Jelic \| Rodriguez-Vieitez \| Savitscheva \| Wall \| Antoni \| Nordberg	Chiotis, Konstantinos	Konstantinos Chiotis, Department NVS, Karolinska Institutet, Stockholm, SE
9	[18] Flortaucipir PET and Diffusion Tensor Tractography Coregistration can Enhance Detection of Brain Changes Associated with Progressive Apraxia of Speech	Gatto \| Duffy \| Utianski \| Clark \| Botha \| Machulda \| Lowe \| Josephs \| Whitwell	Gatto, Rodolfo G.	Rodolfo G. Gatto, Division of Neurology, Mayo Clinic, Rochester, MN, US
10	Towards a simplified flortaucipir-PET read method for assessing tau burden	Tunali \| Iaccarino \| Ducker \| Patel \| DiFabbio \| Kowaleski \| Arora \| Kim \| Lu \| Pontecorvo \| Shcherbinin	Tunali, Ilke	Ilke Tunali, Eli Lilly and Company, Indianapolis, IN, US
12	Digital clock drawing performance is associated with tau deposition measured with PET in preclinical Alzheimers disease	Fu \| Rentz \| Mayblyum \| Thibault \| Buckley \| Das \| Papp \| Sperling \| Penney \| Davis \| Johnson \| Price	Fu, Jessie Fang-Lu	Jessie Fang-Lu Fu, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, US
13	[18F]RO-948 Tau PET Retention and Correlation with Fluid Biomarkers in the Early AD Continuum	Shekari \| González Escalante \| Milà-Alomà \| Falcon \| Niñerola-Baizán \| Tonietto \| Borroni \| Klein \| J. Ashton \| K. Karikari \| Lantero-Rodriguez \| Snellman \| Ortiz \| Vanmechelen \| Minguillón \| Fauria \| Perissinotti \| Molinuevo \| Zetterberg \| Blennow \| Grau-Rivera \| Suárez-Calvet \| Domingo Gispert	Shekari, Mahnaz	Mahnaz Shekari, Barcelona?eta Brain Research Center (BBRC), Pasqual Maragall Foundation,, Barcelona, ES
14	Regional tau predicts glucose hypometabolism in autosomal dominant Alzheimers disease: Findings from the Colombia-Boston (COLBOS) biomarker study	Langella \| Kaplan \| Baena \| Londono \| Munera \| Vila-Castelar \| Alvarez \| Vidal \| Properzi \| Sanchez \| Sperling \| Johnson \| Lopera \| Hanseeuw \| Quiroz	Langella, Stephanie	Stephanie Langella, Massachusetts General Hospital / Harvard Medical School, Boston, MA, US
15	Is tau PET a robust biomarker for chronic traumatic encephalopathy?	Krishnadas \| Doré \| Lamb \| Guzman \| Ponsford \| Hicks \| Williams \| Feizpour \| Villemagne \| Rowe	Krishnadas, Natasha	Natasha Krishnadas, Florey Institute of Neurosciences & Mental Health, Melbourne, AU
16	Centiloid scale measure of amyloid PET by CT of PET/CT equipment	Matsuda \| Hanyu \| Kaneko	Matsuda, Hiroshi	Hiroshi Matsuda, Fukushima Medical University, Fukushima, JP
17	Successful cognitive aging is associated with less brain atrophy and lower tau deposition	Pezzoli \| Giorgio \| Harrison \| Martersteck \| Jagust	Pezzoli, Stefania	Stefania Pezzoli, Helen Wills Neuroscience Institute, University of California, Berkeley, CA, US
18	Subcortical flortaucipir PET and susceptibility analyses to differentiate progressive supranuclear palsy clinical variants and corticobasal syndrome	Satoh \| Arani \| Schwarz \| Senjem \| Ali \| Jack \| Lowe \| Josephs \| Whitwell	Satoh, Ryota	Ryota Satoh, Mayo Clinic, Rochester, MN, US
19	Temporal associations of plasma and PET Alzheimers disease biomarkers using a non-linear mixed effects model	Cogswell \| Lundt \| Therneau \| Graff-Radford \| Schwarz \| Senjem \| Gunter \| Vemuri \| Petersen \| Jack Jr	Cogswell, Petrice	Petrice Cogswell, Department of Radiology, Mayo Clinic, Rochester, MN, US
20	Beta-amyloid accumulates at a faster rate in individuals with Down syndrome	McVea \| DiFilippo \| McLachlan \| Murali \| Zammit \| Johnson \| Betthauser \| Stone \| Tudorascu \| Laymon \| Klunk \| Cohen \| Handen \| Christian	McVea, Andrew	Andrew McVea, University of Wisconsin - Madison, Madison, WI, US
21	Magnitude of MK6240 off-target binding correlated with spill-in effects in target regions	McVea \| DiFilippo \| McLachlan \| Johnson \| Betthauser \| Christian	McVea, Andrew	Andrew McVea, University of Wisconsin - Madison, Madison, WI, US
22	Amyloid and tau pathology associated with different cognitive declines in cognitively normal older people	Chen \| Juarez \| Baker \| Harrison \| Landau \| Jagust	Chen, Xi	Xi Chen, University of California, Berkeley, Berkeley, CA, US
23	Future amyloid accumulation status affects the preservation of peripheral whole-blood gene co-expression networks at baseline in asymptomatic Alzheimers disease	Luckett \| Zielonka \| Schaeverbeke \| Adamczuk \| Van Laere \| Dupont \| Cleynen \| Vandenberghe	Luckett, Emma	Emma Luckett, Laboratory for Cognitive Neurology, KU Leuven, Leuven, BE
24	Validation of [18f]florbetaben PET quantitation based on the analysis of 15 software pipelines	Jovalekic \| Roé-Vellvé \| Koglin \| Lagos Quintana \| Nelson \| Diemling \| Lilja \| Gómez González \| Doré \| Bourgeat \| Whittington \| Gunn \| Stephens \| Bullich	Stephens, Andrew	Andrew Stephens, Life Molecular Imaging, Berlin, DE
25	Preprocessing 10,700 real-world amyloid-PET scans from the IDEAS study: the Good, the Bad and the Ugly	Mejia Perez \| Mundada \| Blazhenets \| Soleimani-Meigooni \| Zeltzer \| Cho \| Ranasinghe \| Windon \| Yadollahikhales \| Iaccarino \| Carrillo \| Gatsonis \| March \| Apgar \| Siegel \| Hilner \| Whitmer \| Rabinovici \| La Joie	Mejia Perez, Jhony	Jhony Mejia Perez, Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, US
26	Longitudinal tau-PET differs between progressive apraxia of speech subtypes	Tetzloff \| Martin \| Duffy \| Clark \| Utianski \| Botha \| Machulda \| Schwarz \| Senjem \| Jack Jr. \| Lowe \| Josephs \| Whitwell	Tetzloff, Katerina A.	Katerina A. Tetzloff, Mayo Clinic Department of Neurology, Rochester, MN, US
27	Cross-sectional PET Analyses in the Longitudinal Early-onset Alzheimers Disease Study (LEADS)	Cho \| Mundada \| Apostolova \| Carrillo \| Shankar \| Amuiri \| Zeltzer \| Windon \| Soleimani Meigooni \| Tanner \| Lawhn Heath \| Aisen \| Eloyan \| Koeppe \| Iaccarino \| Dickerson \| La Joie \| Rabinovici	Cho, Hanna	Hanna Cho, Memory and Aging Center, UCSF Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, US
28	Dynamic amyloid PET: relationships to tau PET and cognition in Alzheimers disease	Raman \| Charniaux \| Murchison \| Fang \| Tzabari \| Liu \| Morris \| Chen \| Joseph-Mathurin \| Ponisio \| Flores \| Kennedy \| Benzinger \| Roberson \| McConathy	Raman, Fabio	Fabio Raman, The University of Alabama at Birmingham, Department of Radiology, Birmingham, AL, US
29	Spatial extent and intensity of Alzheimer-associated tau PET burden is greater in agrammatic than logopenic primary progressive aphasia	Martersteck \| Sridhar \| Coventry \| Weintraub \| Mesulam \| Rogalski	Martersteck, Adam	Adam Martersteck, Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University, Chicago, IL, US
30	Comparing PI2620 and Flortaucipir in Progressive Supranuclear Palsy Subjects	Thomas \| Blazhenets \| La Joie \| Rabinovici \| Heuer \| Jagust \| Boxer \| Baker	Thomas, Wesley	Wesley Thomas, University of California, Berkeley, Berkeley, CA, US
31	Assessing a universal neocortical mask for Centiloid quantification	Bourgeat \| Dore \| Rowe \| Benzinger \| Tosun \| Goyal \| LaMontagne \| Jin \| Weiner \| Morris \| Masters \| Fripp \| Villemagne	Feizpour, Azadeh	Azadeh Feizpour, Austin Health, AU
32	Relationships between Neuronal Hyperactivity, Stress Susceptibility, and Alzheimers Disease pathology	Sharp \| Razlighi \| Oh	Oh, Hwamee	Hwamee Oh, Carney Institute for Brain Science, Brown University, Providence, RI, US
33	A/T/N, cognitive, health and lifestyle differences across white matter hyperintensities groups in aged 45-85 years adults: Results from the Wisconsin Registry for Alzheimer's Prevention (WRAP)	Du \| Burghy \| Cody \| Hermann \| Jonaitis \| Betthauser \| Chin \| Cadman \| Rivera-Rivera \| Peret \| Johnson \| Rowley \| Pompa \| Lose \| Christian \| Janelidze \| Hansson \| Johnson \| Eisenmenger \| Koscik	Du, Lianlian	Lianlian Du, Wisconsin Alzheimer's Institute, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, US
34	Medial temporal 18F-MK6240 levels are associated with global graph characteristics of functional connectivity from high-density EEG in the asymptomatic and prodromal stage of Alzheimer disease	Spruyt \| Reinartz \| Meade \| Khachatryan \| Van Hulle \| Van Laere \| Dupont \| Vandenberghe	Spruyt, Laure	Laure Spruyt, Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, BE
35	Longitudinal PET assessments of tau pathologies in progressive supranuclear palsy with 18F-florzolotau (PM-PBB3/APN-1607)	Endo \| Takado \| Tagai \| Matsuoka \| Kokubo \| Hirata \| Kataoka \| Oya \| Matsumoto \| Kurose \| Ichihashi \| Hatano \| Saiki \| Hirano \| Nakano \| Furukawa \| Takeda \| Isose \| Imai \| Yagi \| Nishida \| Yuasa \| Ono \| Seki \| Takahata \| Tokuda \| Shinotoh \| Shimada \| Kawamura \| Zhang \| Higuchi	Endo, Hironobu	Hironobu Endo, Department of Functional Brain Imaging, Institute for Quantum Medial Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Chiba, JP
36	Head-to-head comparison of tau PET tracers [18F]PI2620 and [18F]RO948 in non-demented individuals with brain amyloid deposition: the TAU-PET FACEHBI cohort	Klein \| Marquié \| Sotolongo-Grau \| Roé-Vellvé \| Bullich \| Tartari \| Sanabria \| García-Sánchez \| Borroni \| Galli \| Tonietto \| Pérez-Martínez \| Tárraga \| Ruiz \| Stephens \| Boada	Klein, Gregory	Gregory Klein, Roche Pharma Research and Early Development, Basel, CH

POSTER SESSIONS: 2A - Thursday, January 12 - 10:45 - 11:30 am; 2B - Thursday, January 12, 4:00 - 4:45 pm

Board #	Title	Authors	Presenter	Presenter/Affiliation
37	Regional [F18]AV1451 uptake in progressive apraxia of speech with and without Alzheimers disease, dysexecutive, and logopenic variants of Alzheimers disease	Switzer \| Corriveau-Lecavalier \| Lowe \| Jones \| Ramanan \| Machulda \| Graff-Radford \| Boeve \| Knopman \| Jack \| Petersen \| Josephs \| Whitwell \| Botha	Switzer, Aaron R	Aaron Switzer, Mayo Clinic, Rochester, MN, US
38	Estimation of Native Spatial Resolution in Clinical Positron Emission Tomography Imaging Data	Galli \| Tonietto \| Klein \| Holiga \| Miho \| Knopf	Galli, Christopher	Christopher Galli, Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F.Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070 Basel, Switzerland, Basel, CH
39	Neuroinflammation Co-Localizes with Tau in Early-Onset MCI patients	Finn \| Appleton \| Bradbury \| Yu \| Faridar \| Beers \| Appel \| Fujita \| Masdeu \| Pascual	Finn, Quentin	Quentin Finn, Nantz National Alzheimer Center, Houston Methodist Neurological and Research Institute, Houston, TX, US
40	Lower locus coeruleus integrity identifies elevated entorhinal tau in low amyloid individuals and is associated with faster clinical progression	Engels-Domínguez \| A. Koops \| M. Riphagen \| F. Smegal \| Bueichekú \| Becker \| M. Kwong \| M. Rentz \| H. Salat \| A. Sperling \| A. Johnson \| I. L. Jacobs	Engels-Domínguez, Nina	Nina Engels-Domínguez, Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, US
41	Substantia nigra 18F-PI-2620 PET signal is associated with motor impairment in Lewy body disease	Winer \| Vossler \| Young \| Romero \| Shahid \| Abdelnour \| Anders \| Shen \| Mormino \| Poston	Winer, Joseph	Joseph Winer, Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA, US
42	Sex differences in A? and tau vulnerability in preclinical Alzheimers disease	Ourry \| St-Onge \| Mohammediyan \| Yakoub \| Soucy \| Poirier \| Breitner \| Villeneuve	Ourry, Valentin	Valentin Ourry, Department of Psychiatry, Faculty of Medicine, McGill University, Montréal, QC, CA
43	Alzheimer's Network for Treatment and Diagnostics (ALZ-NET): Defining the future of Alzheimer's treatment, imaging and care	Whitlow \| March \| Rabinovici \| Rafii \| Atri \| Daffner \| Edelmayer \| Gatsonis \| Lopez \| Porsteinsson \| Possin \| Salloway \| Sano \| Snyder \| Vukmir \| Wilkins \| Windon \| Carrillo	Whitlow, Christopher	Christopher Whitlow, American College of Radiology, Reston, VA, US
44	Acquisition time corrections for SUVR analyses of [18F]-PI-2620	Young \| Vossler \| Winer \| Romero \| Anders \| Shen \| Poston \| Davidzon \| Mormino	Young, Christina	Christina Young, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, US
45	Longitudinal accumulation of white matter lesions is associated with amyloidosis and brain atrophy, but not systemic vascular risk	Shirzadi \| Schultz \| Yau \| Fitzpatrick \| Levin \| Joseph-Mathurin \| Kantarci \| Preboske \| Jack Jr. \| Farlow \| Fagan \| Hassenstab \| Jucker \| Morris \| Xiong \| Karch \| Levey \| Gordon \| Schofield \| Salloway \| Perrin \| McDade \| Levin \| Cruchaga \| Allegri \| Fox \| Goate \| Day \| Koeppe \| Noble \| Chui \| Berman \| Mori \| Sanchez-Valle \| Lee \| Rosa-Neto \| Ruthirakuhan \| Wu \| Swardfager \| Benzinger \| Sohrabi \| Martins \| Schultz \| Bateman \| Johnson \| Sperling \| Greenberg \| Chhatwal	Shirzadi, Zahra	Zahra Shirzadi, Massachusetts General Hospital, Brigham and womens hospital, Harvard Medical School, Boston, MA, US
46	Sex-associated differences in cerebrospinal fluid and plasma biomarkers in early-onset Alzheimer's disease	Nemes \| Logan \| Dage \| Fagan \| Hammers \| Manchella \| Eloyan \| Kostadinova \| Foroud \| Zetterberg \| Koeppe \| Aisen \| Carrillo \| Rabinovici \| Dickerson \| Apostolova	Nemes, Sára	Sára Nemes, Indiana University School of Medicine, Indiana, IN, US
47	Correlations between Janssen Simoa plasma p217+tau and tau PET in participants screened for Janssens Au?onomy Ph2 anti-tau trial in early Alzheimers Disease	Saad \| Triana-Blatzer \| Moughadam \| Slemmon \| Henley \| Kolb	Saad, Ziad S.	Ziad S. Saad, Neuroscience Biomarkers and Global Imaging, Janssen R&D, Johnson & Johnson, San Diego, CA, US
48	Sleep apnea and poor sleep quality are linked to tau deposition in older women at higher risk for Alzheimers	Lui \| Shepherd \| Wang \| Bernier \| Bosompra \| DeYoung \| Malhotra \| Sundermann \| Banks	Lui, Kitty	Kitty Lui, San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, US
49	Machine Learning Based Tau Positivity Classification On Tau-PET Scans Considers Biological Variability And Can Aid In Decision Making	Gebre \| Rial \| Raghavan \| Sparrman \| Wiste \| Schwarz \| Lowe \| Graff-Radford \| Knopman \| Petersen \| Schöll \| Jack Jr \| Vemuri	Gebre, Robel	Robel Gebre Department of Radiology Mayo Clinic, Rochester
50	Impact of florbetaben acquisition timing on SUVR and centiloid values	Johns \| Kennedy \| Young \| Younes \| Vossler \| Poston \| Davidzon \| Mormino	Johns, Emily	Emily Johns, Stanford University School of Medicine, Stanford, CA, US
51	Postmortem In Vitro Binding of APN-1607 to PSP and HC Globus Pallidus Homogenates	Tempest \| Margolin \| Paget \| Campbell \| Navia	Tempest, Paul	Paul Tempest, Aprinoia Theraputics, Cambridge, MA, US
52	Histone deacetylase tracer [11C]Martinostat behaves differently in amyloid versus synuclein rich regions in dementia with Lewy bodies	Goodheart \| Yoo \| Striar \| Quan \| Wey \| Wang \| Gomperts	Goodheart, Anna	Anna Goodheart, Department of Neurology, Massachusetts General Hospital, Boston, MA, US
53	A CenTauR scale based on 18F-MK6240	Dore \| Bourgeat \| Leuzy \| Huang \| Krishnadas \| Feizpour \| Fripp \| Villemagne \| Rowe	Krishnadas, Natasha	Natasha Krishnadas, Florey Department of Neurosciences & Mental Health, The University of Melbourne, Melbourne, AU
54	Tau accumulation across the Alzheimer's disease continuum: an 18F-MK6240 AIBL study	Krishnadas \| Doré \| Robertson \| Ward \| Fowler \| Masters \| Bourgeat \| Fripp \| Villemagne \| Rowe	Krishnadas, Natasha	Natasha Krishnadas, Florey Department of Neurosciences & Mental Health, The University of Melbourne, Melbourne, AU
55	Multi-modal analysis of myelin and neurofilament light chain in individuals at risk for Alzheimers disease using MRI, PET, and CSF biomarker assessments	Yang \| Dean III \| Betthauser \| Carlsson \| Johnson \| Blennow \| Zetterberg \| Alexander \| Bendlin	Yang, Kao Lee	Kao Lee Yang, Wisconsin Alzheimer's Disease Research Center, University of Wisconsin, Madison, WI, US
56	The gut microbiota metabolite trimethylamine n-oxide is associated with white matter degeneration on the Alzheimers disease continuum	Moody \| Heston \| Zarbock \| Blennow \| Zetterberg \| Rey \| Ulland \| Bendlin	Moody, Jason	Jason Moody, Wisconsin Alzheimers Disease Research Center, University of Wisconsin-Madison, Madison, WI, US
57	In vivo measures of fibrillar beta-amyloid pathology limits cognitive plasticity in healthy aging: A multi-center intervention study.	Bischof \| Fellerhoff \| Giehl \| Drzezga	Bischof, Gerard	Gerard Bischof, University of Cologne, University Hospital of Cologne, Department of Nuclear Medicine, Multimodal Neuroimaging Group, Cologne, Germany, Cologne, DE
58	One Year Longitudinal Change of Tau Accumulation on [18F]PI-2620 PET in Alzheimer Spectrum	Oh \| Oh \| Lee \| Oh \| Seo \| Roh \| Lee \| Kim	Oh, Minyoung	Minyoung Oh, Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KR
59	The role of vascular pathology in the association between amyloid-? and tau in cognitively unimpaired individuals	Coomans \| van Westen \| Pichet Binette \| Strandberg \| Spotorno \| Palmqvist \| Stomrud \| Ossenkoppele \| Hansson	Coomans, Emma	Emma Coomans, Radiology & Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, NL
60	Dual biomarker amyloid PET for improved subtype and stage inference	Scott \| Coath \| Dickson \| McQuaid \| Cash \| Schott	Scott, Catherine J	Catherine J Scott, Institute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, GB
61	Standardization of Tau PET using the CenTauR Scale: Preliminary findings from BioFINDER-2 using [18F]RO948 and [18F]Flortaucipir	Leuzy \| Doré \| Klein \| Baker \| Carrillo \| Charil \| Collins \| Collins \| Haeberlein \| Henscheid \| Hostetler \| Higuchi \| Muthinson \| Iaacarino \| Irizarry \| Jagust \| Johnson \| Karten \| Kolb \| Lopresti \| Ossenkoppele \| Pascoal \| Pappas \| Pontecorvo \| Rabinovici \| Raket \| Bohorquez \| Saad \| Stephens \| Mathotaarachchi \| Mintun \| Sivakuraman \| Smith \| Rowe \| Villemagne \| Hansson	Leuzy, Antoine	Antoine Leuzy, Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden, Malmö, SE
62	Plasma GFAP and NFL are correlated with measures of global cognition in EOAD and EOnonAD	Kostadinova \| Hammers \| Logan \| Manchella \| Nemes \| Fagan \| Foroud \| Zetterberg \| Kramer \| Aisen \| Carrillo \| Rabinovici \| Dickerson \| Apostolova \| Dage	Kostadinova, Ralitsa V.	Ralitsa V. Kostadinova, Indiana University School of Medicine, Indianapolis, IN, US
63	Comparisons of plasma biomarkers with 18F-Florzolotau PET in AD continuum a pilot study	Huang \| Ing-Tsung \| Lin \| Huang	Huang, Kuo-Lun	Kuo-Lun Huang, Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, TW
64	Validating Tau PET Staging Schemes in Relation to Cognitive Outcomes	Hammers \| Lin \| Logan \| Risacher \| Schwarz \| Apostolova	Hammers, Dustin	Dustin Hammers, Indiana University School of Medicine, Department of Neurology, Indianapolis, IN, US
65	Shared variance between FDG metabolism and PiB tracer delivery is not predictive of cognitive decline in preclinical AD	Mayblyum \| Shirzadi \| Becker \| Chhatwal \| Farrell \| Jacobs \| Guehl \| El Fakhri \| Sperling \| Price \| Johnson \| Schultz \| Hanseeuw	Mayblyum, Danielle	Danielle Mayblyum, Massachusetts General Hospital, Boston, MA, US
66	Amyloid and tau PET are associated with plasma phosphorylated tau 181 and glial fibrillary acidic protein in a sample of heterogeneous dementia syndromes	Cousins \| Phillips \| Das \| Fulop \| Nasrallah \| O'Brien \| McMillan \| Irwin \| Massimo \| Grossman \| Wolk	Phillips, Jeffrey	Jeffrey Phillips, University of Pennsylvania, Philadelphia, PA, US
67	Combined and independent effects of hyperphosphorylation of tau on microglial activation	Rahmouni \| Therriault \| Tissot \| L. Benedet \| Ashton \| Triana-Baltzer \| Lussier \| Servaes \| Macedo \| Stevenson \| Stevenson \| Kunach \| Fernandez-Arias \| Wang \| Gauthier \| Kolb \| Karikari \| Zetterberg \| Blennow \| Pascoal \| Rosa-Neto	Rahmouni, Nesrine	Nesrine Rahmouni, Translational Neuroimaging Laboratory, McGill Research Centre for Studies in Aging, Montreal, QC, CA
68	Cognitive impairment is more closely associated with the regional extension of F18MK6240 tau-PET signal than with PET signal intensity or CSF tau measures	Hanseeuw \| Gerard \| Malotaux \| Colmant \| Quenon \| Ivanoiu \| Lhommel	Hanseeuw, Bernard	Bernard Hanseeuw, Cliniques Universitaires Saint-Luc, Brussels, BE
69	Disentangling spatial-temporal remote interaction between tau and Amyloid-? proteins in different stages of tau aggregations	Hojjati \| Feiz \| Nayak \| Shteingart \| Ozoria \| Fernández \| Devanand \| Luchsinger \| Stern \| Razlighi	Hojjati, Seyed Hani	Seyed Hani Hojjati, Weill Cornell Medicine, New York, NY, US
70	Predictors of Discordance Between Pre-PET Clinical Diagnosis and Amyloid-PET Results in the Imaging DementiaEvidence for Amyloid Scanning (IDEAS) Study	Tanner \| La Joie \| Hanna \| Iaccarino \| Allen \| Siegel \| Hillner \| Whitmer \| Gatsonis \| Carrillo \| Rabinovici	Tanner, Jeremy	Jeremy Tanner, Memory and Aging Center, University of California San Francisco, San Francisco, CA, US
71	Mid-life atherosclerotic cardiovascular disease risk score and late-life AT(N) measures	Saeed \| Chang \| Royse \| Lopresti \| Snitz \| Villemagne \| Reis \| Lopez \| Cohen	Cohen, Ann	Ann Cohen, University of Pittsburgh School of Medicine, Pittsburgh, PA, US
72	A clinical diagnosis of Alzheimer's disease and CSF-based tau positivity are both associated with lower locus coeruleus metabolism	Koops \| Dutta \| Becker \| Van Egroo \| Riphagen \| Prokopiou \| Hanseeuw \| Sperling \| El Fakhri \| Johnson \| Jacobs	Koops, Elouise A.	Elouise A. Koops, Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Boston, MA, US

POSTER SESSIONS: 3A - Friday, January 13, 9:15 - 10:00 am; 3B - Friday, January 13, 3:15 - 4:00 pm

Board #	Title	Authors	Presenter	Presenter/Affiliation
73	Motion and partial volume corrections in dynamic [18F]-MK6240 PET imaging	Tiss \| Gong \| Lois \| Becker \| Thibault \| Guehl \| Xia \| Normandin \| Ouyang \| Johnson \| El Fakhri	Gong, Kuang	Kuang Gong, Gordon Center for Medical Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA, US
74	Encoding, consolidation and retrieval deficits are differentially shaped by tau and atrophy in the Alzheimer’s disease spectrum	Fernandez \| Therriault \| Lussier \| Bezgin \| Tissot \| Servaes \| Wang \| Matothaarachchi \| Stevenson \| Rahmouni \| Kang \| Pallen \| Kunach \| Quispialaya \| Margherita-Poltronetti \| Pascoal \| Rosa-Neto	Fernandez Arais, Jaime	Jaime Fernandez Arias, Montreal Neurological Institute, McGill University
75	Comorbid medical conditions, anxiety, and amyloid-β pathology in cognitively unimpaired older adults	Abiose \| Young \| Winer \| Deters \| Mormino	Abiose, Olamide	Olamide Abiose, Stanford University School of Medicine Department of Neurology & Neurological Sciences, Stanford, CA, US
76	Defining and characterizing neocortical tau resistance in preclinical Alzheimer’s disease	Buckley \| Klinger \| Boyle \| Coughlan \| Hanseeuw \| Yang \| Amariglio \| Rentz \| Townsend \| Farrell \| Jacobs \| Shirzadi \| Yau \| Price \| Chhatwal \| Schultz \| Hohman \| Donohue \| Properzi \| Johnson \| Sperling	Buckley, Rachel	Rachel Buckley, Massachusetts General Hospital, Department of Neurology, Boston, MA, US
77	Development and evaluation of image preprocessing pipelines for the Centiloid method	Luo \| Minhas \| Rubenstein \| Situ \| Royse \| Ances \| Christian \| Cohen \| Handen \| Klunk \| Tudorascu \| Zamon \| Laymon	Luo, Weiquan	Weiquan Luo, Department of Radiology, University of Pittsburgh, Pittsburgh, PA, US
78	Cognitively estimated disease time: Associations with amyloid and tau burden in the Harvard Aging Brain Study	Townsend \| Properzi \| Betthauser \| Klinger \| Boyle \| Coughlan \| Hanseeuw \| Yang \| Amariglio \| Farrell \| Jacobs \| Shirzadi \| Yau \| Price \| Chhatwal \| Rentz \| Johnson \| Sperling \| Schultz \| Buckley	Townsend, Diana	Diana Townsend, Department of Neurology, Massachusetts General Hospital, Boston, MA, US
79	Synergistic interaction between sex, amyloid and phosphorylated tau predicts the longitudinal progression of tau tangles	Wang \| Therriault \| Servaes \| Tissot \| Fernandez Arias \| Rahmouni \| Macedo \| Stevenson \| Stevenson \| Haeger \| Hosseini \| Nazneen \| Rosa-Neto	Wang, Yi-Ting	Yi-Ting Wang, McGill Centre for Studies in Aging, Montreal, QC, CA
80	[18F]PI-2620 binding patterns in patients with suspected AD- and FTLD-tauopathies	Blazhenets \| Soleimani-Meigooni \| Thomas \| Brendel \| Vento \| VandeVrede \| Heuer \| Ljubenkov \| Rojas \| Chen \| Iaccarino \| Mundada \| Litvan \| Grossman \| Boeve \| Pantelyat \| Tartaglia \| Irwin \| Dickerson \| Baker \| Boxer \| Rabinovici \| La Joie	Blazhenets, Ganna	Ganna Blazhenets, Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, US
81	Regional analysis of change in synaptic density over time by cognitive status	DiFilippo \| Mcvea \| Mclachlan \| Pasquesi \| Davenport-Sis \| Jonaitis \| Ennis \| Betthauser \| Engle \| Johnson \| Bendlin \| Christian	DiFilippo, Alexandra	Alexandra DiFilippo, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, US
82	Regional tau profiles in early tau pathology populations	Kotari \| Morris \| Svaldi \| Southekal \| Lu \| Pontecorvo \| Collins \| Shcherbinin \| Neuroimaging Initiative	Kotari, Vikas	Vikas Kotari, Eli Lilly and Company, Indianapolis, IN, US
83	[18F]MK-6240 tau-PET in an Aβ-enriched sample from the 1946 British birth cohort - Insight 46	Coath \| Markiewicz \| Modat \| Scott \| Malone \| Thomas \| Dickson \| Schöll \| Ourselin \| Richards \| Fox \| Cash \| Schott	Coath, William	William Coath, Dementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, GB
84	Longitudinal trajectories of depressive symptoms and regional amyloid accumulation (PiB PET) in clinically normal older adults	Munro \| Farrell \| Hanseeuw \| Buckley \| Properzi \| Vannini \| Amariglio \| Quiroz \| Blacker \| Rentz \| Sperling \| Johnson \| Marshall \| Gatchel	Munro, Catherine	Catherine Munro, Brigham and Women's Hospital, Boston, MA, US
85	Improving sub-threshold PiB fidelity using relative radioligand delivery	Properzi \| Shirzadi \| Buckley \| Klinger \| Hanseeuw \| Amariglio \| Rentz \| Farrell \| Price \| Chhatwal \| Marshall \| Gatchel \| Johnson \| Sperling \| Schultz	Properzi, Michael	Michael Properzi, Massachusetts General Hospital, Boston, MA, US
86	Improved prediction of preclinical cognitive decline using amyloid PET spatial extent	Farrell \| Thibault \| Becker \| Price \| Hanseeuw \| Buckley \| Papp \| Jacobs \| Rentz \| Sperling \| Johnson	Farrell, Michelle E.	Michelle E. Farrell, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US
87	18F-MK-6240 Tau PET as a Potential Biomarker for Chronic Traumatic Encephalopathy	Alosco \| Mundada \| La Joie \| Asken \| Nowinski \| Smith \| Culhane \| Shankar \| Amuiri \| Pettway \| Iaccarino \| Windon \| Tripodis \| Mercier \| Kowall \| Stein \| Grinberg \| McKee \| Stern \| Miller \| Mez \| Killiany \| Rabinovici	Asken, Breton	Breton Asken, PhD, University of Florida, Department of Clinical and Health Psychology
88	Psychosis and tau burden across the AD continuum	Johnson* \| Ziaggi* \| Huey, MD \| Kreisl, MD \| Talmasov, MD \| Lao, PhD	Johnson, Aubrey S.	Aubrey Johnson, Columbia University Irving Medical Center
89	Classifying cognitive resilience to differing levels of Alzheimer’s disease pathology	Boyle \| Townsend \| Klinger \| Coughlan \| Hanseeuw \| Yang \| Amariglio \| Farrell \| Jacobs \| Shirzadi \| Yau \| Price \| Chhatwal \| Schultz \| Hohman \| Donohue \| Properzi \| Rentz \| Johnson \| Sperling \| Buckley	Boyle, Rory	Rory Boyle, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, US
90	Cerebrospinal fluid neurofilament light predicts increased amyloid, tau, and decreased grey matter density	Manchella \| Logan \| Dage \| Hammers \| Nemes \| Kostadinova \| Eloyan \| Mundada \| La Joie \| Iaccarino \| Fagan \| Foroud \| Zetterberg \| Koeppe \| Aisen \| Carrillo \| Rabinovici \| Dickerson \| Apostolova	Manchella, Mohit	Mohit Manchella, Indiana University School of Medicine, Indianapolis, IN, US
91	Unhealthy white matter connectivity in African American and non-Hispanic white older adults	Royse \| Snitz \| Hengenius \| Huppert \| Roush \| Cisneros \| Potopenko \| Becker \| Cohen \| Shaaban	Royse, Sarah	Sarah Royse, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, US
92	Locus coeruleus integrity as neural substrate providing resilience against cognitive decline in the face of Alzheimer’s disease pathology	Jacobs \| Papp \| Buckley \| Riphagen \| Hanseeuw \| Boyle \| Donovan \| Rentz \| Sperling \| Johnson	Jacobs, Heidi IL	Heidi IL Jacobs, Massachusetts General Hospital, Gordon Center for Medical Imaging, Boston, MA, US
93	Lower locus coeruleus integrity predicts diminished practice effects in cognitively normal older individuals	Smegal \| Schneider \| Jutten \| Rentz \| Johnson \| Sperling \| Papp \| Jacobs	Smegal, Lindsay	Lindsay Smegal, Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital/ Harvard Medical School, Boston, MA, US
94	PET-based Braak staging predicts neuropsychiatric burden in the Alzheimer’s disease continuum	Macedo \| Tissot \| Therriault \| Servaes \| Rahmouni \| Fernandez-Arias \| Z. Lussier \| Stevenson \| Wang \| Quispialaya Socualaya \| Nazneen \| Ali Hosseini \| Kunach \| Haeger \| Stevenson \| Vitali \| A. Pascoal \| Rosa-Neto	C. Macedo, Arthur	Arthur C. Macedo, McGill University, Montreal, QC, CA
95	A computational model to study the combined effect of neuronal connectivity loss and tauopathy progression	Rahimabadi \| Soucy \| Benali	Rahimabadi, Arsalan	Arsalan Rahimabadi, PERFORM Centre, Concordia University, Montreal, QC, CA
96	Simulated dose reduction in longitudinal [18F]MK-6240 PET	McLachlan \| McVea \| DiFilippo \| Schöll \| Betthauser \| Johnson \| Christian	McLachlan, Max	Max McLachlan, Department of Medical Physics, University of Wisconsin – Madison, School of Medicine and Public Health, Madison, WI, US
97	Regional amyloid change improves prediction of future tau progression over global metrics	Thibault \| Farrell \| Properzi \| Mayblyum \| Hanseewu \| Healy \| Price \| Becker \| Sperling \| Johnson	Thibault, Emma	Emma Thibault, Massachusetts General Hospital, Boston, MA, US
99	Rates of tau PET accumulation along the amyloid timeline in Alzheimer’s disease	Cody \| Langhough \| Christian \| Betthauser \| Johnson	Cody, Karly	Karly Cody, Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin-Madison, Madison, WI, US
100	Body mass index, pathological tau, and cognition in preclinical AD: Could women with high BMI be protected?	Wang \| Sundermann \| Buckley \| Reas \| McEvoy \| Banks	Wang, Xin	Xin Wang, Department of Neurosciences, University of California, San Diego., La Jolla, CA, US
101	Amyloid drives later tau accumulation for fast progressors in early Braak stages	Servaes \| Therriault \| Tissot \| Lussier \| Bezgin \| Wang \| Stevenson \| Rahmouni \| Stevenson \| Pallen \| Kunach \| Fernandez Arias \| Cassa Macedo \| Hosseini \| Pascoal \| Gauthier \| Rosa-Neto	Servaes, Stijn	Stijn Servaes, Translational Neuroimaging Laboratory, McGill Research Centre for Studies in Aging, Montreal, QC, CA
102	Brain-wide and AD-risk genetic expression: A descriptive study	Hobbs \| McCullough \| Millar \| Gordon	Hobbs, Diana	Diana Hobbs, Washington University in St. Louis, St. Louis, MO, US
103	Behavioral brain networks underlying the effect of Alzheimer’s pathology on cognition	Ziontz \| Harrison \| Jagust	Ziontz, Jacob	Jacob Ziontz, Helen Wills Neuroscience Institute, University of California Berkeley,, Berkeley, CA, US
104	Exploration of 18F-Florzolotau tau PET distribution patterns using machine learning approach in AD	Huang \| Lee \| Lin \| Huang \| Hsu \| Chang \| Huang \| Hsiao	Huang, Shao-Yi	Shao-Yi Huang, Medical Imaging & Radiological Sciences and Healthy Aging Research Center, Chang Gung University, Taoyuan, TW
105	The interplay of vascular disease, peripheral interleukin-6, beta-amyloid, and memory in older adults	Rizvi \| Adams \| Sathishkumar \| Kim \| Larson \| McMillan \| Brickman \| Mapstone \| Thomas \| Greenia \| Corrada \| Kawas \| Yassa	Rizvi, Batool	Batool Rizvi, University of California, Irvine, Irvine, CA, US
106	Gut microbiome composition is associated with cortical amyloid burden in a preclinical human cohort	Heston \| González \| Betthauser \| Johnson \| Asthana \| Knight \| Kaddurah-Daouk \| Rey \| Bendlin	Heston, Margo	Margo Heston, Wisconsin Alzheimer's Disease Research Center, Madison, WI, US
107	Study on MR-free template-based spatial normalization for Tau PET Image Quantitation using 18F-Florzolotau	Lee \| Huang \| Lin \| Huang \| Huang \| Wu \| Chang \| Hsiao	Lee, Zih-Ning	Zih-Ning Lee, Medical Imaging & Radiological Sciences and Healthy Aging Research Center, Chang Gung University, Taoyuan, TW
108	β-Amyloid in World Trade Center responders: Result indicate age-related toxic encephalopathy mediated by an immunogenic amyloid response	Clouston \| Vaska \| Huang \| Kritikos \| Zhou	Vaska, Paul	Paul Vaska, Stony Brook University, Stony Brook, NY, US
109	[18F]MK-6240 PET/MRI Test-Retest performance in cognitively normal elderly subjects	Lois \| Fanglu Fu \| Salvatore \| Huell \| Izquierdo Garcia \| Garimella \| Dickerson \| Johnson \| Catana \| Price	Lois, Cristina	Cristina Lois, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, US