HAI 2020 POSTER SESSIONS
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Please note that we reserve the right to re-arrange the poster allocation.
POSTER SESSIONS: 1A - Wednesday, January 15 - 9:45 - 10:30 am; 1B - Wednesday, January 15, 4:00 - 4:45 pm
BOARD | Title | Author Name | Presenter |
---|---|---|---|
1 | Label-free x-ray method for estimating brain amyloid load | Badano | Dahal | Ghammraoui | Badano |
29 | Application of an epidemic spreading model to characterize amyloid beta accumulation in dutosomal dominant Alzheimer’s disease mutation carriers | Levitis | Vogel | Kiar | Funck | Iturria-Medina | Evans | Levitis |
12 | Voxel-wise relationships between white matter hyperintensities (WMH) and multimodal neuroimaging biomarkers of Alzheimer’s disease | Gaubert | Lange | Garnier-Crussard | Bougacha | Gonneaud | de Flores | Tomadesso | Mézenge | Landeau | de La Sayette | Chételat | Wirth | Lange |
46 | PET imaging of [11C]MPC-6827, a micrtoubule-based PET tracer in murine models of Alzheimer's disease | Solingapuram sai | Macauley | Whitlow | Mintz | Craft | Solingapuram sai |
4 | A pons cluster detected by a data-driven approach may serve as a favorable reference region for 18F-PI-2620 Tau PET analysis | Bischof | van Eimeren | Koglin | Müller | Bullich | Perrotin | Stephens | Drzezga | Bischof |
11 | Influence of iron and beta-amyloid deposition on entorhinal cortex and hippocampal subfield volumes in the aging brain | Foster | Kennedy | Rodrigue | Foster |
17 | [11C]PiB amyloid quantification and choice of reference region | Heeman | Hendriks | van Berckel | Lopes Alves | Lammertsma | Yaqub | Heeman |
47 | Quantifying the relationship between the brain distributions of tau and local atrophy to inter-regional connectivity based on individual human data | Soucy | Mohammadi | Rosa-Neto | Pascoal | Savard | Kang | Therriault | Benali | Soucy |
52 | PET beta-amyloid deposition in healthy older adults is associated with decreased lure discrimination on a spatial mnemonic similarity task | Webb | Foster | Horn | Kennedy | Rodrigue | Webb |
21 | Concordance of visual and quantitative assessments of baseline amyloid scans in the GRADUATE gantenerumab studies | Klein | Delmar | Voyle | Hesterman | Petrulli | Ovens | Baudler | Fontoura | Doody | Kerchner | Klein |
54 | Tau pathology and relative cerebral blood flow are independently associated with cognition in Alzheimer’s disease | Wolters | Visser | Verfaillie | Coomans | Timmers | Tuncel | Boellaard | Windhorst | Scheltens | van der Flier | Ossenkoppele | van Berckel | Wolters |
53 | Socioeconomic status mediates racial differences seen using the A-T(N) Framework | Wisch | Hudson | Coble | Xiong | Babulal | Gordon | Flores | Dincer | Benzinger | Morris | Ances | Ances |
27 | Probability Template Method for Analysis of Down Syndrome Amyloid PET | Laymon | Minhas | James | Christian | Cohen | Klunk | Tudorascu | Royse | Zaman | Handen | Laymon |
36 | Association between Cerebral Amyloid Accumulation and Synaptic Density in Alzheimer’s Disease: A Multitracer PET Study | O Dell | Mecca | Chen | Godek | Harris | Bartlett | Banks | Kominek | Zhao | Naganawa | Toyonaga | Lu | Nabulsi | Vander Wyk | Varma | Arnsten | Huang | Carson | van Dyck | O'Dell |
10 | Quantifying off-target skull binding in [18F]Flortaucipir PET studies | Flores | Gordon | Su | Christensen | Dincer | Adedokun | Hornbeck | Morris | Benzinger | Flores |
40 | MIND MAPS: Assessment of the mitochondrial - endoplasmic reticulum - synaptic axis in neurodegeneration by [18F]BCPP-EF, [11C]SA4503 and [11C]UCB-J PET imaging | Rabiner | Mansur | Venkataraman | Price | Wilson | Pagano | Clarke | Lewis | Matthews | Rowe | Brooks | Middleton | Politis | Rohrer | Comley | Evans | Martarello | Chen | Schwarz | Schmidt | Tsukada | Passchier | Gunn | Consortium | Rabiner |
14 | Amyloid binding is associated with markers of white matter microstructure in patients with significant white matter disease | Goubran | Ozzoude | Adamo | Zukotynski | Bocti | Borrie | Chertkow | Frayne | Gao | Hsiung | Kiss | Laforce | Noseworthy | Prato | Ramirez | Sahlas | Scott | Smith | Sossi | Strother | Swartz | Tardif | Thiel | Soucy | Black | Goubran |
20 | Hippocampal volume mediates the relationship between amyloidosis and amyloid-sensitive cognitive composite in preclinical AD | Kim | Hahn | Kim | Kim | Chin | Seo | Hahn |
7 | Tau pathology and synaptic loss are closely associated in Alzheimer’s disease in vivo: a combined [18F]flortaucipir and [11C]UCB-J PET study | Coomans | Verfaillie | Wolters | Tuncel | Golla | Ossenkoppele | Scheper | Schober | Sweeney | Ryan | Schuit | Windhorst | Scheltens | Boellaard | van Berckel | Coomans |
5 | Early detection of amyloid load using 18F-Florbetaben PET | Bullich | Roé-Vellvé | Marquié | Villemagne | Sanabria | Tartari | Sotolongo | Doré | Koglin | Müller | Perrotin | De Santi | Tárraga | Stephens | Rowe | Seibyl | Boada | Bullich |
8 | Longitudinal dynamic [18F]flortaucipir PET reveals increased early stage tau pathology in individuals with subjective cognitive decline | Coomans | Visser | Ossenkoppele | Verfaillie | Timmers | Wolters | Tuncel | Schmidt | Boellaard | Windhorst | Scheltens | van der Flier | van Berckel | Coomans |
34 | Sex-specific differences in [18F]AV-1451 off-target retention | Minhas | Yu | Laymon | Lopresti | Snitz | Tudorascu | Aizenstein | Lopez | Mathis | Klunk | Cohen | Minhas |
33 | MRI and PET data harmonization in a two-site Down syndrome study | Minhas | Yang | Muschelli | Laymon | Zammit | Ellison | Johnson | Mathis | Crainiceanu | Klunk | Handen | Christian | Cohen | Tudorascu | Tudorascu |
28 | Visualizing brain astrocytes - characterization of 3H-BU99008 in human AD brain tissue | Lemoine | Malarte | Koistinen | Nordberg | Lemoine |
24 | Validation of highly sensitive and specific florbetaben positivity thresholds using ADNI participants and young controls | Landau | Korman | Bullich | De Santi | Stephens | Koeppe | Jagust | Landau |
51 | Association Between [18F]NAV4694 PET Amyloid-β Measures and Fluid Biomarkers Across the Spectrum of Alzheimer Disease | Wang | Pascoal | Therriault | Benedet | Lussier | Savard | Kang | Tissot | Gauthier | Rosa-Neto | Wang |
55 | Amyloid Load trajectories and chronicity reveal groups of early amyloid accumulators in Down syndrome | Zammit | Koscik | Laymon | Betthauser | Tudorascu | Cohen | Minhas | Johnson | Zaman | Mathis | Klunk | Handen | Christian | Zammit |
56 | Hippocampal-retrosplenial cortex connectivity predicts tau accumulation in cognitively normal older adults | Ziontz | Adams | Baker | Jagust | Ziontz |
42 | Linking APOE ε4, blood-brain barrier dysfunction and inflammation to Alzheimer’s pathology | Riphagen | Ramakers | Freeze | Pagen | Hanseeuw | Verbeek | Verhey | Jacobs | Riphagen |
9 | Preliminary evaluation of synaptic vesicle protein SV2A imaging with [11C]UCB-J across the cognitive spectrum | DiFilippo | Murali | McKinney | Davenport | Barnhart | Engle | Betthauser | Johnson | Bendlin | Christian | DiFilippo |
25 | Additive contribution of white matter hyperintensity to amyloid and neurodegeneration on cognitive decline in a diverse, community-based cohort of older adults | Lao | Chesebro | Colon | Igwe | Gu | Schupf | Manly | Stern | Mayeux | Brickman | Lao |
6 | Age-related neural dedifferentiation of episodic memory networks is related to beta-amyloid and tau pathology in normal aging | Cassady | Adams | Maass | Harrison | Baker | Jagust | Cassady |
23 | Genetically informed quantitative Gradient Recalled Echo MRI reveals brain tissue in hippocampal subfields void of neurons in mild Alzheimer disease | Kothapalli | Benzinger | Aschenbrenner | Goyal | Fagan | Raichle | Morris | Yablonskiy | Kothapalli |
2 | Examining regional MK-6240 patterns and associations with amyloid and cognitive decline | Betthauser | Cody | Koscik | Jonaitis | Erickson | Converse | Murali | Barnhart | Stone | Mueller | Clark | Asthana | Christian | Johnson | Betthauser |
50 | Neuropsychiatric symptoms in cognitively impaired individuals are correlated with tau deposition | Tissot | Therriault | Pascoal | Chamoun | Lussier | Savard | Mathotaarachchi | L. Benedet | Thomas | Rosa-Neto | Gauthier | Tissot |
38 | Amyloid PET variability due to variation in MRI protocol and anatomical segmentation | Palombit | Manber | Joules | Wolz | Manber |
48 | Monitoring disease pathophysiology using multiparametric PET acquisitions: The McGill TRIAD Cohort | Stevenson | Chamoun | A. Pascoal | L. Benedet | Kang | Mathotaarachchi | Therriault | Thomas | Savard | Tissot | Lussier | Vinet-Celluci | Rahmouni | Gagné | Joung | Sbeiti | Shin | Vitali | Gauthier | Rosa-Neto | Stevenson |
39 | The impact of automatic Tau PET processing on uptake variability and power analysis in AD | Palombit | Manber | Joules | Wolz | Manber |
32 | PiB tracer delivery decreases overtime in preclinical AD – impact for amyloid pathology measurement | Mayblyum | Becker | Schultz | Farrell | Jacobs | Rubinstein | Sanchez | Thibault | Sperling | Price | Johnson | Hanseeuw | Mayblyum |
15 | CSF dynamics explains discrepant PET-CSF AD biomarkers | Gunter | Senjem | Cogswell | Schwarz | Lowe | Kantarci | Vemuri | Elder | Botha | Graff-Radford | Jones | Mielke | Graff-Radford | Knopman | Petersen | Jack, Jr. | Gunter |
45 | Development of a Qualitative Read Method for Characterizing the Presence and Extent of Brain Tau Deposition Using [18F]MK-6240 PET Imaging | Seibyl | Salinas | Rajagovindan | Hutchison | Beaver | Martarello | Seibyl |
26 | White matter hyperintensities are related to tau burden in late-Braak stage regions | Lao | Laing | Igwe | Chesebro | Kreisl | Moreno | Luchsinger | Brickman | Lao |
44 | MCI patients demonstrate reliably increasing 18F-AV1451 PET uptake across three exams | Scott | Adamczuk | Gorman | Runkle | Suhy | Scott |
37 | A clinically applicable proxy for gold standard quantification of amyloid-beta in Alzheimer’s disease: Bolus plus constant infusion 18F-AV45 PET | Ottoy | Kang | Verhaeghe | Stroobants | Bouhachi | Hsiao | Stevenson | Rahmouni | Chartrand | Massarweh | Soucy | Gauthier | Rosa-Neto | Staelens | Ottoy |
13 | Beta-amyloid deposition and its association with metabolism | Gordon | Goyal | Couture | Flores | Morris | Raichle | Benzinger | Vlassenko | Gordon |
19 | Data-Driven Biological Pattern Scoring of Flortaucipir Scans Outperforms ROIs | Jones | Graff-Radford | Botha | Senjem | Wiste | Josephs | Whitwell | Kantarci | Boeve | Petersen | Knopman | Lowe | Jack | Jones |
3 | Transcriptomic profiling of brain amyloidosis using peripheral blood-based gene expression | Bharthur Sanjay | Svaldi | Apostolova | Bharthur Sanjay |
35 | Polygenic Risk for Cerebrospinal Fluid (CSF) Amyloid Predicts Brain Amyloid in Clinically Normal Older Adults | Moore | Dumitrescu | Schultz | Raghavan | Johnson | Mayeux | Sperling | Hohman | Mormino | Moore |
31 | Age prediction and amyloid deposition in SuperAgers | Martersteck | Besson | Sridhar | Makowski-Woidan | Parrish | Katsaggelos | Mesulam | Bandt | Rogalski | Martersteck |
22 | Regional amyloid burden is associated with higher quantitative T1 in discrete hippocampal sub-regions | Kohli | Yang | Vogt | Asthana | Betthauser | Alexander | Christian | Johnson | Kecskemeti | Bendlin | Kohli |
49 | Interaction between amyloid and neuroinflammation on apathy along the Alzheimer’s disease spectrum | Tissot | Kang | L. Benedet | Rahmouni | Pascoal | Chamoun | Therriault | Lussier | Savard | Mathotaarachchi | Thomas | Gauthier | Rosa-Neto | Tissot |
41 | Associations between Neurogranin and imaging biomarkers of Alzheimer’s disease | Rahmouni | L.Benedet | Nicholas J. | Tissot | Pascoal | Kvartsberg | Chamoun | Kang | Lussier | Therriault | Stevenson | Savard | Mathotaarachchi | Thomas | Gauthier | Zetterberg | Blennow | Rosa-Neto | Rahmouni |
43 | Heterogeneity of tau PET signal in the sub-nuclei of the amygdala | Rubinstein | Jacobs | Augustinack | Properzi | Becker | Mayblyum | Thibault | Sanchez | Schultz | Hanseeuw | Gomez-Isla | Lois-Gomez | Price | Sperling | Johnson | Rubinstein |
18 | Retrospective prediction of amyloid accumulation trajectories in a risk-enriched Alzheimer’s disease cohort with sequential neural network | Hwang | Koscik | Betthauser | Tao | Kim | Johnson | Singh | Hwang |
16 | Predicting future amyloid spread with machine learning using longitudinal [C11]PiB-PET in preclinical Alzheimer's disease | Hao | Vogt | Meng | Hwang | Koscik | Betthauser | Christian | Johnson | Bendlin | Singh | Singh |
30 | Phantom-based harmonization of PET image reconstruction parameters between the Siemens ECAT HR+ PET and the GE Discovery MI PET/CT scanners | Lois | Grogg | El Fakri | Johnson | Price | Lois |
POSTER SESSIONS: 2A - Thursday, January 16 - 10:45 - 11:30 am; 2B - Thursday, January 16, 4:00 - 4:45 pm
BOARD | Title | Author Name | Presenter |
---|---|---|---|
100 | Entorhinal tau pathology is associated with medial temporal lobe hyperactivity in aging | Adams | Maass | Berron | Harrison | Baker | Thomas | Stanfill | Jagust | Adams |
80 | Sex differences in the rates of cognitive decline associated with temporal lobe FTP-PET signal: findings from the Harvard Aging Brain Study | Buckley | Properzi | Schultz | Jacobs | Kirn | Rentz | Hanseeuw | Johnson | Sperling | Buckley |
73 | Imaging synaptic and mitochondrial function in frontotemporal dementia using [11C]UCB-J, [18F]BCPP-EF and [11C]SA4503 PET | Clarke | Mansur | Passchier | Lewis | Evans | Chen | Schwarz | Takano | Gunn | Cash | Rabiner | Rohrer | Clarke |
105 | Longitudinal associations between lifestyle risk, β-amyloid, and cognition in late-midlife | Cody | Koscik | Birdsill | Berman | Erickson | Chin | Clark | Christian | Betthauser | Johnson | Cody |
62 | Correlation of QSM signal with Alzheimer’s disease biomarkers | Cogswell | Wiste | Senjem | Therneau | Lowe | Knopman | Botha | Graff-Radford | Jones | Kantarci | Vemuri | Ferman | Boeve | Mielke | Schwarz | Gunter | Petersen | Jack | Cogswell |
71 | Quantitative regional amyloid burden and white matter changes in preclinical Alzheimer’s Disease | Collij | Top | Stickney | Ingala | Tomassen | Lopes Alves | Yaqub | Wink | Van 't Ent | Scheltens | Van Berckel | Visser | Barkhof | Den Braber | AMYPAD consortium | Collij |
70 | Individual variability in the cortical distribution of elevated 18F-AV1451 and 11C-PIB in a heterogeneous sample of AD patients | Collins | Eckbo | McGinnis | Dickerson | Collins |
93 | Neuroinflammation in Alzheimer’s disease patients and correlates with amyloid and tau deposition | Edison | Leng | Dani | Brooks | Edison |
85 | Sex differences in regional tau deposition in cognitively impaired patients with Alzheimer’s disease | Edwards | La Joie | Iaccarino | Kim | Baker | Casaletto | Miller | Jagust | Rabinovici | Edwards |
69 | Higher microglia biomarker levels are associated with slower rates of amyloid-beta accumulation in humans and in a transgenic mouse model of amyloid-beta | Ewers | Brendel | Suarez-Calvet | Biechele | Sacher | Blume | Haass | Franzmeier | Ewers |
99 | Early declines in learning and executive function associated with accumulating Aβ not tau in low PIB adults | Farrell | Papp | Buckley | Jacobs | Schultz | Properzi | Hanseeuw | Rentz | Johnson | Sperling | Farrell |
68 | Association of tau tangle burden with depressive symptoms in community dwelling older adults: a longitudinal study | Gatchel | Marshall | Yang | Donovan | Buckley | Properzi | Quiroz | Rabin | Vannini | Amariglio | Chhatwal | Rentz | Blacker | Sperling | Johnson | Hanseeuw | Gatchel |
78 | Amyloid deposition affects the topography of cortical thinning in Lewy Body Disease | Ye | Touroutoglou | Brickhouse | Katz | Growdon | Johnson | Dickerson | Gomperts | Gomperts |
107 | Data-driven approach to characterization of tau accumulation in Braak staging groups | Groh | Svaldi | Stage | Sanjay | Risacher | Saykin | Apostolova | Groh |
77 | A sensitive composite model to determine subtle cognitive differences in preclinical Alzheimer’s disease | Hahn | Kim | Kim | Jang | Kim | Na | Chin | Seo | Hahn |
61 | Defining a Centiloid scale threshold predicting long-term progression to dementia in patients attending the Memory Clinic: an F18-Flutemetamol amyloid-PET study | Hanseeuw | Malotaux | Dricot | Quenon | Cerman | Buckley | Farrar | Ivanoiu | Lhommel | Hanseeuw |
92 | Amyloid deposition disrupts functional connectivity and graph properties within the Default Mode Network | Ingala | Wink | Prent | van 't Ent | Tomassen | ten Kate | Konijnenberg | Collij | Yaqub | Scheltens | de Goes | Teunissen | Barkhof | van Berckel | Visser | den Braber | den Braber |
74 | First-in-human evaluations of [11C]PS13 for imaging COX-1 and [11C]MC1 for imaging COX-2 | Kim | Juarez Anaya | Lee | Hong | Miller | Telu | Morse | Singh | Cortes-Salva | Henry | Ruiz-Perdomo | Montero Santamaria | Liow | Zoghbi | Fujita | Katz | Pike | Innis | Kim |
91 | Prevalence of amyloid PET positivity in cognitively normal the East Asian populations | Kim | Jung | Na | Kim | Won | Seo | Kim |
64 | Evaluating the relationships among odor identification, tau pathology and neuroinflammation in Alzheimer’s disease | Klein | Yan | Johnson | Tomljanovic | Zou | Polly | Honig | Brickman | Stern | Lee | Kreisl | Klein |
67 | Distinct effects of APOE ε2 on Aβ in Alzheimer- and Vascular-type cognitive impairment | Lee | Lee | Park | Choe | Park | Cheon | Hahn | Ossenkoppele | Kim | Kim | Yoo | Jang | Cho | Kim | Kim | Jung | Park | DeCarli | Weiner | Yun | Na | Seo | Lee |
79 | Longitudinal change in amyloid load over a 5-year period in cognitively healthy APOE4 carriers versus non-carriers: Effect of reference region | Luckett | Adamczuk | Schaeverbeke | Gabel | Van Laere | Dupont | Vandenberghe | Luckett |
113 | Mild behavioral impairment is associated with tau pathology in cognitively impaired elderly individuals | Lussier | Pascoal | Therriault | Tissot | Savard | Benedet | Mathotaarachchi | Stevenson | Ismail | Rosa-Neto | Gauthier | Lussier |
114 | Modeling the trajectory of tau deposition in autosomal-dominant Alzheimer’s disease using the high-affinity tau tracer [18F]MK6240 | Lussier | Therriault | Pascoal | Savard | Mathotaarachchi | Robb | Stevenson | Gauthier | Rosa-Neto | Lussier |
101 | Clinicopathological confirmation of 123I-FP-CIT SPECT (ioflupane) quantification methods in a spectrum of neurodegenerative syndromes and associated pathologies | Maltais | Jordan | Miyagawa | Lesnick | Przybelski | Min | Dickson | Murray | Kantarci | Boeve | Lowe | Maltais |
106 | Exploring relationships between tau burden and naming in the aphasic variant of Alzheimer’s disease | Martersteck | Sridhar | Coventry | Eldes | Wood | Kim | Mesulam | Rogalski | Martersteck |
65 | Elevated soluble phosphorylated tau is a marker of early amyloid PiB PET abnormalities and accumulation | McDade | Li | Joseph-Mathurin | Benzinger | Fagan | Xiong | Barthélemy | Bateman | McDade |
112 | A clinically-relevant scheme for qualitatively rating tau PET, amyloid PET, and MRI in neurodegenerative cognitive presentations | McGinnis | Collins | Eckbo | Brickhouse | Dickerson | McGinnis |
66 | Cerebrospinal fluid and PET measures of tau pathology may indicate different stages of AD pathological progression | Meyer | Pichet Binette | Gonneaud | Breitner | Villeneuve | Meyer |
96 | Use of the plasma amyloid-beta 42/40 ratio for predicting amyloid PET in a community-based population | Mielke | Algeciras-Schimnich | Campbell | Syrjanen | Knopman | Jack Jr. | Peterson | Mielke |
111 | Cerebrospinal fluid matrix metalloproteinases are associated with compromised white matter microstructure among older adults: the Vanderbilt memory & aging project | Moore | Pechman | Acosta | Bell | Anderson | Landman | Blennow | Zetterberg | Gifford | Hohman | Jefferson | Moore |
94 | Development of new alpha7 nicotinic receptor ASEM analogs for PET imaging | Nordberg | Lemoine | Mohan | Kuang | Nag | Jia | Miranda Azpiazu | Datta | Arakawa | Varnäs | Ågren | Långström | Halldin | Nordberg |
108 | Associations between Alzheimer’s disease biomarkers and cognition among cognitively normal older adults | Oh | Correia | Salloway | Oh |
75 | [11C]MK-6884 PET tracer for M4 muscarinic cholinergic receptors in Alzheimer’s disease: comparison with [18F]FDG PET | Pascual | Zanotti-Fregonara | Yu | Funk | Arbones | Wang | Li | Cheng | Anderson | Hostetler | Basile | Masdeu | Pascual |
81 | Amyloid and tau PET burden are associated with white matter bundle abnormalities in asymptomatic individuals at risk of Alzheimer’s disease | Pichet Binette | Theaud | Gonneaud | Poirier | Descoteaux | Villeneuve | Pichet Binette |
104 | Increased risk of Alzheimer’s disease in alcohol use disorder is not mediated by amyloid-beta in a middle-aged cross-sectional cohort | Royse | Himes | Minhas | Lopresti | Flanigan | Narendran | Royse |
86 | Cross-sectional and longitudinal non-dichotomized CSF/PET Aβ data support existence of “CSF+ first” vs. “PET+ first” pathways of Aβ biomarkers changes | Sala | Nordberg | Rodriguez-Vieitez | Sala |
82 | NeuroToolkit CSF biomarkers track the progression of Alzheimer’s disease at very early stages and show that inflammatory markers modulate cerebral amyloid accumulation | Salvadó | Molinuevo | Milà-Alomà | Blennow | Zetterberg | Operto | Falcón | Batrla | Battle | Buckley | Farrar | Minguillon | Fauria | Sánchez-Benavides | Suárez-Calvet | Gispert | the ALFA study | Salvadó |
83 | T1rho MRI measurement of amyloid plaque burden in cognitively unimpaired individuals: preliminary results in the ALFA+ cohort | Falcón | Montesinos | Grau-Rivera | Suárez-Calvet | Puig-Pijoan | Cascales | Navalpotro-Gomez | Fernández-Lebrero | Sánchez-Valle | Gelpi | Sanfeliu | Rojas | Perissinotti | Niñerola-Baizán | Salvadó | Minguillon | Fauria | Molinuevo | Sánchez-González | Gispert | the ALFA study | Salvadó |
84 | Preliminary quantitative results of the AMYPAD prognostic and Natural History Study | Gispert | Lopes-Alves | Gray | Buckley | Collij | Heeman | Salvadó | Scheltens | Frisoni | Ritchie | Vellas | Stephens | Ford | Molinuevo | Farrar | Barkhof | the AMYPAD Consortium | Salvadó |
72 | Effect of genetic risk, brain amyloid and hippocampal volume on normal variation in episodic memory performance in middle-aged and older adults | Schaeverbeke | Gabel | Adamczuk | Van Laere | Dupont | Vandenberghe | Schaeverbeke |
103 | White matter disruption is an early and progressive feature of pre-symptomatic Dutch-type hereditary cerebral amyloid angiopathy | Scott | Schultz | Sohrabi | Gardener | Taddei | Bateman | Benzinger | Johnson | Sperling | Martins | Greenberg | Chhatwal | Investigators | Scott |
88 | Head-to-head comparison of F-Florbetaben and F-Flutemetamol uptakes in the cortex, striatum and white matter | Seo | Cho | Moon | Choe | Na | Seo |
90 | PI-2620 Tau PET is associated with amyloid-beta levels in scans from subjects of the elenbecestat MissionAD program | Stephens | Bullich | Mueller | Berndt | De Santi | Scott | Adamczuk | Suhy | Kaplow | Giroux | Krause | Chang | Albala | Stephens |
110 | Using famous faces to investigate the neural systems involved in name retrieval | Tennant | Jagust | La Joie | Adams | Winer | Tennant |
109 | In vivo association of mitochondrial dysfunction with tau pathology in early Alzheimer’s disease | Terada | Therriault | Min Su | Savard | Ouchi | Rosa-Neto | Terada |
102 | Preliminary results: PiB and MK6240 regional PET measures associated with digitized clock drawing performance | Mayblyum | Thibault | Moody | Farrell | Jiang | Jacobs | Rubinstein | Sanchez | Katz | Sperling | Papp | Rentz | Johnson | Thibault |
97 | Associations between longitudinal cognitive measures and cross-sectional tau in adults with Down syndrome | Tudorascu | Comer | Zammit | Laymon | Minhas | Ellison | Zaman | Ances | Johnson | Mathis | Klunk | Christian | Handen | Hartley | Cohen | Tudorascu |
60 | Longitudinal flortaucipir ([18F]AV-1451) PET uptake in Semantic Dementia | Utianski | Whitwell | Martin | Botha | Schwarz | Duffy | Clark | Spychalla | Senjem | Petersen | Knopman | Jack, Jr. | Lowe | Josephs | Utianski |
76 | Assessing Aβ, tau, and reactive astrocytosis in aging and AD | Villemagne | Harada | Doré | Furumoto | Mulligan | Kudo | Krishnadas | Huang | Yanai | Rowe | Okamura | Villemagne |
63 | Developing a novel alpha-synuclein (a-syn) positron emission tomography (PET) tracer for the diagnosis of Parkinson’s disease (PD) and other a-synucleinopathies | Vokali | Molette | Tsika | Ravache | Rodriguez | Jürgens | Melo dos Santos | Sandiego | Russell | Gunn | Darmency | Piorkowska | Poli | Kroth | Capotosti | Hliva | Sol | Marek | Stöhr | Lowe | Pfeifer | Kosco-Vilbois | Vokali |
95 | Biological underpinnings of typical and atypical Alzheimer’s dementia phenotypes | Whitwell | Tosakulwong | Graff-Radford | Weigand | Schwarz | Senjem | Ertekin-Taner | Jones | Boeve | Knopman | Jack | Petersen | Lowe | Josephs | Whitwell |
89 | Sleep impairment predicts longitudinal accumulation of β-amyloid | Winer | Mander | Jagust | Walker | Winer |
87 | Personality and amyloid accumulation in cognitively normal aging | Yoon | Baker | Korman | Tennant | Harrison | Jagust | Yoon |
98 | Associations of amyloid deposition and FDG uptake in aging and cognitively impaired elders with and without moderate to severe periventricular white matter hyperintensities | Zukotynski | Gaudet | Kuo | Adamo | Goubran | Scott | Bocti | Borrie | Chertkow | Frayne | Hsiung | Laforce | Noseworthy | Prato | Sahlas | Smith | Sossi | Thiel | Soucy | Tardif | Black | Zukotynski |
POSTER SESSIONS: 3A - Friday, January 17, 9:15 - 10:00 am; 3B - Friday, January 17, 3:15 - 4:00 pm
BOARD | Title | Author Name | Presenter |
---|---|---|---|
132 | CSF P-tau detects cerebral tau accumulation earlier than tau PET in amyloid positive elderly adults | Guo | Jagust | Landau | Guo |
162 | Association between cerebrospinal fluid neurofilament light chain and markers of neurofibrillary pathophysiology: Findings from the Knight Alzheimer Disease Research Center | Schultz | Schindler | Chen | Sutphen | Morris | Fagan | Gordon | Benzinger | Schultz |
130 | Functional connectivity brain architecture predicts the rate of tau accumulation in Alzheimer’s disease | Franzmeier | Neitzel | Rubinski | Smith | Strandberg | Ossenkoppele | Hansson | Ewers | Franzmeier |
154 | Widespread amyloid is necessary to detect tau-PET signal beyond the entorhinal cortex and cognitive decline | Ozlen | Binette | Köbe | Meyer | Villeneuve | Ozlen |
135 | Preclinical characterization of [18F]THK-5562, a novel tau PET tracer with little off-target binding | Harada | Lerdsirisuk | Yiqing | Ezura | Shimizu | Morito | Arai | Yanai | Kudo | Furumoto | Okamura | Harada |
155 | Using 18F-Flortaucipir visual assessment to define T-status in the AT(N) framework: evaluation of intra- and inter-rater reliability | Provost | Iaccarino | Soleimani-Meigooni | Lesman-Segev | La Joie | Edwards | Strom | Pham | Mellinger | Janabi | Baker | Jagust | Rabinovici | Provost |
156 | Defining T-status in the AT(N) framework: comparison of 18F-Flortaucipir visual assessment, SUVR quantification and CSF pTau | Provost | Iaccarino | Soleimani-Meigooni | Lesman-Segev | La Joie | Mattsson | Hansson | Eichenlaub | Edwards | Strom | Pham | Mellinger | Janabi | Baker | Jagust | Rabinovici | Provost |
133 | Amyloid, tau, and atrophy in preclinical Alzheimer’s disease: a longitudinal study | Hanseeuw | Jacobs | Schultz | Buckley | Properzi | Farrell | Scott | Hampton | Sanchez | Sperling | Johnson | Hanseeuw |
126 | Quantifying tau PET imaging reliably in the presence of off-target binding | Chen | Gordon | McCullough | Zaza | Mejias | Dincer | Flores | Keefe | Paulick | Jackson | Koudelis | Su | Morris | Benzinger | Chen |
157 | Plasma neurofilament light is associated with regional tau tangle burden in autosomal dominant Alzheimer's disease: findings from the COLBOS Project | Quiroz | Zetterberg | Reiman | Sanchez | Guzman-Velez | Fox-Fuller | Arboleda-Velasquez | Baena | Gatchel | Sperling | Johnson | Blennow | Lopera | Quiroz |
159 | Measuring increases of tau pathology in Alzheimer's disease using [18F]GTP1 (Genentech tau probe 1) PET imaging | Sanabria Bohorquez | Baker | Manser | Toth | Teng | Marik | Weimer | Sanabria Bohorquez |
131 | How innocent is PART? Mesial temporal tau is associated with worse cognitive performance in Aβ-negative cognitively normal individuals | Groot | Groot |
137 | In vivo amyloid-PET and tau-PET evidence in early-onset Alzheimer’s Disease: taking the LEADS | Iaccarino | La Joie | Lesman-Segev | Soleimani-Meigooni | Provost | Collins | Aisen | Borowski | Eloyan | Fagan | Foroud | Gatsonis | Jack Jr. | Kramer | Saykin | Toga | Vemuri | Day | Graff-Radford | Honig | Jones | Masdeu | Mendez | Onyike | Rogalski | Salloway | Wolk | Wingo | Koeppe | Dickerson | Apostolova | Carrillo | Rabinovici | Iaccarino |
174 | Associations of tau pathology and functional connectivity with retrospective cognitive change among cognitively normal older adults | Shafer | Bilgel | Ziontz | Wong | Resnick | Ziontz |
158 | Application of tau PET as a biomarker of Alzheimer’s disease in therapeutic trials: a pharmaceutical industry perspective | Salinas | Lohith | Guo | Wooten | Tulip | Sanjeewa | Comley | Sur | Hostetler | Beaver | Martarello | Salinas |
167 | Intrinsic connectivity of the human brain provides scaffold for tau aggregation in Alzheimer's disease | Therriault | Pascoal | Savard | Mathotaarachchi | Benedet | Chamoun | Gauthier | Saha-Chaudhuri | Massarweh | Rosa-Neto | Therriault |
138 | Multimodal in vivo investigation of amyloid and tau biomarkers associations with cerebrospinal fluid NfL and YKL40 levels | Iaccarino | La Joie | Edwards | Lesman-Segev | Strom | Pham | Chaudhary | Fenton | Jerome | Janabi | Baker | Miller | Jagust | Fagan | Rabinovici | Iaccarino |
122 | Perfusion-phase 18F-PI-2620 tau-PET imaging as a surrogate marker of neuronal injury | Brendel | Beyer | Nitschmann | Barthel | van Eimeren | Marek | Song | Palleis | Respondek | Sauerbeck | Hammes | Barbe | Onur | Jessen | Saur | Schroeter | Rumpf | Rullmann | Schildan | Patt | Neumaier | Barret | Madonia | Russel | Stephens | Roeber | Herms | Bötzel | Levin | Classen | Hoeglinger | Bartenstein | Villemagne | Drzezga | Seibyl | Sabri | Brendel |
123 | Binding characteristics of 18F-PI-2620 differentiate the clinically predicted tau isoform in suspected 3/4-repeat and 4-repeat tauopathies | Brendel | Song | Beyer | Barthel | van Eimeren | Marek | Palleis | Kaiser | Respondek | Sauerbeck | Hammes | Barbe | Onur | Jessen | Saur | Schroeter | Rumpf | Rullmann | Schildan | Patt | Neumaier | Barret | Madonia | Russel | Stephens | Roeber | Herms | Bötzel | Levin | Classen | Hoeglinger | Bartenstein | Villemagne | Drzezga | Seibyl | Sabri | Brendel |
124 | 18F-PI2620 tau-PET for assessment of heterogeneous neuropathology in corticobasal syndrome | Brendel | Palleis | Prix | Gehmeyr | Bötzel | Danek | Höllerhage | Sauerbeck | Beyer | Nitschmann | Song | Stephens | Barthel | Patt | Sabri | Drzezga | van Eimeren | Villemagne | Bartenstein | Perneczky | Haass | Levin | Hoeglinger | Brendel |
173 | [18F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer’s disease | Wolters | Ossenkoppele | Verfaillie | Coomans | Timmers | Visser | Tuncel | Golla | Windhorst | Boellaard | van der Flier | Teunissen | Scheltens | van Berckel | Wolters |
170 | Hippocampal tau accumulation predicts individual differences in episodic memory in cognitively normal older adults | Trelle | Toueg | Castillo | Channappa | Corso | Hunt | Jayakumar | Nadiadwala | Guo | Azevedo | Shin | Davidson | Deutsch | Hall | Sha | Fredericks | Kerchner | Carr | Chin | Wagner | Mormino | Trelle |
128 | Comparison of quantitative cutoff methods for [18F]AV-1451 | Minhas | Laymon | Lopresti | Snitz | Tudorascu | Aizenstein | Lopez | Mathis | Klunk | Cohen | Cohen |
134 | Increased levels and phosphorylation of soluble tau proteins occur earlier than changes in Tau PET in Alzheimer’s disease | Hansson | Andersson | Janelidze | Ossenkoppele | Insel | Strandberg | Zetterberg | Blennow | Chai | Dage | Stomrud | Smith | Palmqvist | Mattsson | Hansson |
172 | Temporal evaluation for maximum CSF pTau181 – [18F]Flortaucipir concordance | Wisch | Gordon | Schindler | Flores | Dincer | Fagan | Benzinger | Morris | Ances | Ances |
121 | Local associations between tau and neurodegeneration among non-demented older adults | Bilgel | Wong | Resnick | Bilgel |
150 | Entorhinal cortical tau accumulation is inversely associated with hippocampal synaptic density in older individuals with normal cognition and early Alzheimer’s disease | Mecca | Chen | Naganawa | Toyonaga | Godek | Harris | Bartlett | Zhao | Gallezot | Nabulsi | Huang | Arnsten | Carson | van Dyck | Mecca |
142 | Comparison of longitudinal change metrics for 18F-RO948 PET among cognitively unimpaired and patients with MCI or AD dementia in the BioFINDER2 study | Klein | Sanabria | Leuzy | Borroni | Mattsson | Palmqvist | Stomrud | Smith | Hansson | Klein |
171 | Temporo-limbic tau burden, as measured by 18F-AV1451, is a correlate of hippocampal volume loss over time | Fischer | Ahnen | Dissertori | Lustermann | Weber | Buck | Kagerer | Gietl | Hock | Unschuld | Unschuld |
127 | [18F]THK5317 imaging as a predictive tool of prospective cognitive decline in prodromal and dementia-stage Alzheimer’s disease | Chiotis | Savitcheva | Poulakis | Saint-Aubert | Wall | Antoni | Nordberg | Chiotis |
143 | Validation of clinical protocols for clinicians analyzing 18F-PI-2620 tau PET/MRI images | Koran | Shams | Adams | Cazevedo | Toueg | Corso | Hunt | Castillo | Hall | Sha | Fredericks | Greicius | Wagner | Zaharchuk | Davidzon | Chin | Mormino | Mormino |
147 | A comparison of ischemic stroke-induced changes on 18F-APN-1607 (18F-PMPBB3) and 18F-THK-5351 uptake patterns | Lin | Hsiao | Huang | Huang | Lin |
161 | Clinical evaluation o[18F]-JNJ-64326067, a candidate PET tracer for the detection of tau pathology in Alzheimer’s disease | Schmidt | Janssens | Moechars | Rombouts | Timmers | Barret | Constantinescu | Madonia | Russell | Sandiego | Kolb | Schmidt |
141 | Prediction of brain tau accumulation in amyloid positive cognitive impairment patients using multimodal biomarkers with machine learning approach | Kim | Park | Park | Kang | Kim | Jang | Kim | Na | Lee | Seo | Kim |
125 | Optimal reference region for the quantification of tau load in the brain using 18F-PI-2620 PET | Bullich | Müller | Roé-Vellvé | Jovalekic | Perrotin | De Santi | Koglin | Stephens | Bullich Roig |
153 | Factors predicting tau PET status in cognitively unimpaired and impaired individuals | Ossenkoppele | Leuzy | Cho | La Joie | Strandberg | Matsson | Palmqvist | Lyoo | Rabinovici | Smith | Hansson | Ossenkoppele |
164 | The rate of accumulation of tau aggregates is higher in females and younger individuals | Smith | Mattsson | Pontecorvo | Devous | Strandberg | Ossenkoppele | Hansson | Smith |
120 | Depression is predicted by tau imaging biomarker among cognitively normal adults | Babulal | Roe | Stout | Rajasekar | Wisch | Benzinger | Morris | Ances | Ances |
169 | Elevated medial temporal lobe Tau PET with 18F-PI2620 in normal controls with “borderline” neuropsychological testing profiles | Toueg | Deutsch | Castillo | Hunt | Corso | Trelle | Harrison | Azevedo | Shen | Anders | Hall | Fredericks | Sha | Davidzon | Chin | Khalighi | Wagner | Mormino | Toueg |
149 | 18F-APN-1607: a promising PET tracer for multiple tauopathies | Margolin | Lin | Tempest | Chen | Marek | Russell | Sandiego | Huang | Hsiao | Tamagnan | Alagille | Guan | Lu | Zuo | Higuchi | Jang | Margolin |
148 | Longitudinal change in [18F]GTP1 SUVR over 18 months depends on baseline SUVR intensity and spatial distribution and shows trends with cognitive decline | Manser | Sanabria Bohorquez | Teng | Baker | Toth | Marik | Weimer | Manser |
168 | Changes in volumetric MRI measures at 12 months significantly correlate with baseline [18F]GTP1 SUVR, but not [18F]GTP1 change | Toth | Sanabria Bohorquez | Manser | Baker | Teng | Marik | Weimer | Toth |
163 | 18F-PM-PBB3 (18F-APN-1607) uptake associates with plasma NfL level and motor disability in patients with progressive supranuclear palsy | Shimada | Tagai | Tatebe | Matsuoka | Kubota | Takahata | Takado | Shinotoh | Yamamoto | Sano | Seki | Nakano | Ono | Hirano | Tempest | Jang | Sahara | Kawamura | Zhang | Tokuda | Higuchi | Shimada |
136 | Comparison of tau PET imaging using 18F-APN-1607 and 18F-THK5351 in Alzheimer's disease patients and normal controls | Hsiao | Lin | Huang | Huang | Hsiao |
145 | Diagnostic performance of [18F]RO948 tau positron emission tomography in the differentiation of AD from other neurodegenerative disorders | Leuzy | Smith | Ossenkoppele | Santillo | Borroni | Klein | Olsson | Jögi | Palmqvist | Mattsson | Strandberg | Stomrud | Hansson | Leuzy |
146 | Longitudinal changes in tau pathology measured by [18F]RO948 tau-PET are associated with elevated CSF P-tau: Preliminary findings from the Swedish BioFINDER-2 study | Leuzy | Klein | Ossenkoppele | Mattsson | Janelidze | Palmqvist | Strandberg | Coloma | Borroni | Stomrud | Smith | Hansson | Leuzy |
166 | Tau positivity: comparing flortaucipir meta-ROI vs maximal single region | Therneau | Schwarz | Wiste | Gunter | Senjem | Lowe | Kantarci | Petersen | Knopman | Mielke | Jones | Jack | Therneau |
165 | Resting state functional connectivity associations with F18-Florbetapir PET versus F18-Flortaucipir PET | Svaldi | Goñi | Stage | Abbas | Dzemidzic | West | Risacher | Saykin | Apostolova | Svaldi |
139 | Activated microglia and amyloid load potentiate tau deposition leading to cognitive dysfunction in Alzheimer’s disease | Kang | Ottoy | Savard | Pascoal | Mathotaarachchi | Benedet | Chamoun | Therriault | Lussier | Tissot | Thomas | Stevenson | Rahmouni | Arias | Wang | Massarweh | Soucy | Gauthier | Rosa-Neto | Kang |
140 | Tauopathy in females is more vulnerable to amyloid or neuroinflammation in Alzheimer’s disease | Kang | Ottoy | Chamoun | Mathotaarachchi | Savard | Benedet | Pascoal | Therriault | Lussier | Tissot | Thomas | Stevenson | Rahmouni | Fernandez-Arias | Wang | Massarweh | Soucy | Gauthier | Rosa-Neto | Kang |
152 | In vivo uptake of 18F-PM-PBB3 (18F-APN-1607) in patients with corticobasal syndrome | Nakano | Shimada | Tagai | Matsuoka | Kubota | Takahata | Takado | Shinotoh | Yamamoto | Sano | Seki | Hirano | Ono | Tempest | Jang | Sahara | Kawamura | Zhang | Kuwabara | Higuchi | Nakano |
144 | Cerebrospinal fluid tau phosphorylated at amino acid 181 or 231: a biomarker comparison in the detection of neurofibrillary tangle pathology in the Alzheimer’s disease spectrum | Benedet | Ashton | Pascoal | Stoops | Francois | Vanmechelen | Karikari | Mathotaarachchi | Savard | Therriault | Chamoun | Zetterberg | Blennow | Rosa-Neto | Benedet |
151 | Mental and physical activity during the uptake period affects off-target binding in extra- and within-brain Tau PET (18F-FTP) | Min | Apgar | Scott | Hol | Lundt | Albertson | Schwarz | Botha | Vemuri | Gunter | Petersen | Jack | Lowe | Min |
160 | Evaluation of tau PET staging in the A4/LEARN Study | Sanchez | Becker | Jacobs | Hanseeuw | Mayblyum | Rubinstein | Thibault | Schultz | Seshadri | Quiroz | Rentz | Price | Sperling | Johnson | the A4 Study Team | Sanchez |
129 | Pilot study on the relationship between 18F-MK-6240 and VBM in early and late stages of AD | Fernandez Arias | Pascoal | Benedet | Thierrault | Su Kang | Savard | Ottoy | Mathotaarachchi | Lussier | Tissot | Thomas | Stevenson | Rahmouni | Wang | Massarweh | Soucy | Gauthier | Rosa-Neto | Fernandez Arias |
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